Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | MMP3 | P08254 | 1/20 | 0.30 |
| ▸ | MMP9 | P14780 | 1/20 | 0.30 |
| ▸ | MMP8 | P22894 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27410375 | 0.77 | MMP1 (0.33) | MMP1MMP2MMP3MMP9MMP8 | |
| SCHEMBL3892672 | 0.74 | DGAT1 (0.38) | — | |
| SCHEMBL2297020 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL1357352 | 0.72 | DGAT1 (0.37) | — | |
| SCHEMBL2787473 | 0.72 | — | — | |
| SCHEMBL16837161 | 0.72 | — | — | |
| SCHEMBL25960852 | 0.72 | — | — | |
| SCHEMBL28860724 | 0.72 | — | — | |
| SCHEMBL29709600 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL7447733 | 0.72 | MMP1 (0.36) | MMP1MMP2MMP3MMP9MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4223753-A1 | AROYL SUBSTITUTED TRICYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | Genfleet Therapeutics (Shanghai) Inc. (CN) | 2023-08-09 | — | — | EP | disclosed |