⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16837161 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL16776689 | 0.98 | NOS2 (0.37) | — | |
| SCHEMBL29709600 | 0.80 | — | — | |
| SCHEMBL2787473 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL2788526 | 0.78 | GGT1 (0.43) | — | |
| SCHEMBL3892672 | 0.78 | DGAT1 (0.38) | — | |
| SCHEMBL20783127 | 0.77 | LMNA (0.35) | — | |
| SCHEMBL14795253 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL1357352 | 0.76 | DGAT1 (0.37) | — | |
| SCHEMBL25961915 | 0.76 | ALOX15 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4223753-A1 | AROYL SUBSTITUTED TRICYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | Genfleet Therapeutics (Shanghai) Inc. (CN) | 2023-08-09 | — | — | EP | disclosed |