Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2297020 | 0.78 | — | — | |
| SCHEMBL25962152 | 0.77 | MMP1 (0.30) | MMP1MMP2MMP3MMP9MMP8 | |
| SCHEMBL28860724 | 0.76 | — | — | |
| SCHEMBL21661357 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL7447733 | 0.76 | MMP1 (0.36) | MMP1MMP2MMP3MMP9MMP8 | |
| SCHEMBL13687263 | 0.76 | RIPK1 (0.37) | MMP1MMP2MMP3MMP9MMP8 | |
| Hydrochloric Acid SCHEMBL31604845 | 0.74 | GGT1 (0.30) | — | |
| SCHEMBL24543403 | 0.74 | EPHX1 (0.38) | KMT2A | |
| SCHEMBL1346149 | 0.72 | — | — | |
| SCHEMBL20648929 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024100139-A1 | USE OF IFN-I ACTIVITY AS A BIOMARKER FOR TLR INHIBITOR TREATMENT | MERCK PATENT GMBH (DE) | 2024-05-16 | — | — | WO | disclosed |