Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 3/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | NR1H3 | Q13133 | 9/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 7/20 | 0.46 |
| ▸ | CASP3 | P42574 | 2/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26458457 | 0.87 | TTR (0.51) | TTRCES1NR1H3NR1H2CASP3 | |
| SCHEMBL14288783 | 0.83 | TTR (0.53) | TTRCES1NR1H3NR1H2CASP3 | |
| SCHEMBL12059599 | 0.76 | NR1H2 (0.59) | TTRCES1NR1H3NR1H2CASP3 | |
| SCHEMBL27019601 | 0.75 | CES1 (0.47) | TTRCES1NR1H3NR1H2CASP3 | |
| SCHEMBL27292538 | 0.73 | KMT2A (0.36) | CASP3CASP6KMT2ASENP8SENP7 | |
| SCHEMBL5502340 | 0.73 | CES1 (0.69) | TTRCES1CASP3CASP6KMT2A | |
| SCHEMBL10262744 | 0.73 | CASP3 (0.59) | TTRCES1NR1H3NR1H2CASP3 | |
| SCHEMBL26223177 | 0.73 | TTR (0.58) | TTRCES1NR1H3NR1H2CASP3 | |
| SCHEMBL9918978 | 0.73 | RNASEH1 (0.49) | TTRCES1CASP3CASP6KMT2A | |
| SCHEMBL7829086 | 0.73 | ALDH1A1 (0.57) | TTRCES1CASP3CASP6KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023141856-A1 | CD3-TARGETING MULTISPECIFIC ANTIBODY AND USE THEREOF | 岩唐生物科技(杭州)有限责任公司 | 2023-08-03 | — | — | WO | disclosed |