Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 4/20 | 0.36 |
| ▸ | EGFR | P00533 | 2/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.36 |
| ▸ | FLT1 | P17948 | 2/20 | 0.36 |
| ▸ | FLT4 | P35916 | 2/20 | 0.36 |
| ▸ | KDR | P35968 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | RBP4 | P02753 | 2/20 | 0.32 |
| ▸ | TTR | P02766 | 2/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.32 |
| ▸ | DDB1 | Q16531 | 4/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 4/20 | 0.32 |
| ▸ | IKZF3 | Q9UKT9 | 3/20 | 0.32 |
| ▸ | DRD2 | P14416 | 2/20 | 0.32 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20612930 | 0.89 | RET (0.36) | SLC6A9EGFRFGFR1FLT1FLT4 | |
| SCHEMBL20613074 | 0.89 | ADRA1D (0.39) | SLC6A9EGFRFGFR1FLT1FLT4 | |
| SCHEMBL25967656 | 0.80 | SLC6A9 (0.38) | SLC6A9EGFRFGFR1FLT1FLT4 | |
| SCHEMBL20613076 | 0.80 | SLC6A9 (0.39) | SLC6A9EGFRFGFR1FLT1FLT4 | |
| SCHEMBL25968327 | 0.77 | SLC6A9 (0.41) | SLC6A9EGFRFGFR1FLT1FLT4 | |
| SCHEMBL25967209 | 0.74 | SLC6A9 (0.39) | SLC6A9EGFRFGFR1FLT1FLT4 | |
| SCHEMBL25966101 | 0.70 | EGFR (0.38) | SLC6A9EGFRFGFR1FLT1FLT4 | |
| SCHEMBL20613067 | 0.69 | EGFR (0.42) | SLC6A9EGFRFGFR1FLT1FLT4 | |
| SCHEMBL25967424 | 0.68 | FFAR4 (0.40) | — | |
| SCHEMBL20612922 | 0.68 | SLC6A9 (0.39) | SLC6A9EGFRFGFR1FLT1FLT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3421454-B9 | PIPERIDINE DERIVATIVE | OTSUKA PHARMA CO LTD (JP) | 2023-08-09 | — | — | EP | disclosed |