Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 4/20 | 0.39 |
| ▸ | HTR1D | P28221 | 4/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.35 |
| ▸ | FLT1 | P17948 | 1/20 | 0.35 |
| ▸ | FLT4 | P35916 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 3/20 | 0.34 |
| ▸ | HTR1B | P28222 | 3/20 | 0.34 |
| ▸ | MGLL | Q99685 | 3/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25968327 | 0.83 | SLC6A9 (0.41) | SLC6A9HTR1DKCNH2EGFRFGFR1 | |
| SCHEMBL20613076 | 0.82 | SLC6A9 (0.39) | SLC6A9HTR1DKCNH2EGFRFGFR1 | |
| SCHEMBL25967656 | 0.79 | SLC6A9 (0.38) | SLC6A9HTR1DKCNH2EGFRFGFR1 | |
| SCHEMBL25966160 | 0.78 | EGFR (0.40) | SLC6A9KCNH2EGFRFGFR1FLT1 | |
| SCHEMBL25967400 | 0.74 | SLC6A9 (0.36) | SLC6A9KCNH2EGFRFGFR1FLT1 | |
| SCHEMBL20613070 | 0.72 | ADRB1 (0.42) | SLC6A9DRD2ADRA1DADRA1AADRA1B | |
| SCHEMBL25967371 | 0.71 | FFAR4 (0.43) | HTR1DC5AR1FFAR4HTR1AHTR1B | |
| SCHEMBL25967424 | 0.70 | FFAR4 (0.40) | HTR1DC5AR1FFAR4HTR1AHTR1B | |
| SCHEMBL25969706 | 0.70 | MGLL (0.43) | SLC6A9HTR1DDRD2HTR1AHTR1B | |
| SCHEMBL25966101 | 0.69 | EGFR (0.38) | SLC6A9KCNH2EGFRFGFR1FLT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3421454-B9 | PIPERIDINE DERIVATIVE | OTSUKA PHARMA CO LTD (JP) | 2023-08-09 | — | — | EP | disclosed |