Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.32 |
| ▸ | FABP7 | O15540 | 2/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
| ▸ | MDM4 | O15151 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25344766 | 1.00 | CASP1 (0.37) | CASP1BACE1MDM2EPHX1FABP5 | |
| SCHEMBL25968518 | 0.94 | CASP1 (0.39) | CASP1BACE1MDM2FABP5FABP7 | |
| SCHEMBL25968600 | 0.91 | NAMPT (0.40) | CASP1EPHX1NAMPTCACNA1I | |
| SCHEMBL25968525 | 0.90 | CASP1 (0.37) | CASP1BACE1MDM2FABP5FABP7 | |
| SCHEMBL25968519 | 0.90 | CASP1 (0.37) | CASP1BACE1FABP5FABP7EPHX2 | |
| SCHEMBL30569816 | 0.89 | CASP1 (0.35) | CASP1NAMPTDPP8DPP9 | |
| SCHEMBL25968589 | 0.88 | NAMPT (0.37) | CASP1BACE1MDM2FABP5FABP7 | |
| SCHEMBL25968522 | 0.88 | SCN9A (0.43) | CASP1 | |
| SCHEMBL25343338 | 0.87 | CASP1 (0.36) | CASP1BACE1FABP5FABP7EPHX2 | |
| SCHEMBL25968596 | 0.87 | CASP1 (0.36) | CASP1BACE1FABP5FABP7EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023154724-A2 | PROCESSES AND COMPOUNDS FOR PREPARING SPIROLIGOMERS | TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2023-08-17 | — | — | WO | disclosed |