Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.33 |
| ▸ | FABP7 | O15540 | 1/20 | 0.32 |
| ▸ | CCR3 | P51677 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | MDM4 | O15151 | 1/20 | 0.32 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.32 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25968518 | 0.94 | CASP1 (0.39) | CASP1FABP5TP53BACE1FABP7 | |
| SCHEMBL25968519 | 0.91 | CASP1 (0.37) | CASP1FABP5ALDH1A1BACE1FABP7 | |
| SCHEMBL25968522 | 0.91 | SCN9A (0.43) | CASP1KCNH2SCN5ASCN9A | |
| SCHEMBL25344766 | 0.90 | CASP1 (0.37) | CASP1FABP5TP53BACE1FABP7 | |
| SCHEMBL25968601 | 0.90 | CASP1 (0.37) | CASP1FABP5TP53BACE1FABP7 | |
| SCHEMBL25968589 | 0.90 | NAMPT (0.37) | CASP1FABP5TP53BACE1FABP7 | |
| SCHEMBL25968596 | 0.89 | CASP1 (0.36) | CASP1FABP5BACE1FABP7EPHX2 | |
| SCHEMBL25343338 | 0.89 | CASP1 (0.36) | CASP1FABP5BACE1FABP7EPHX2 | |
| SCHEMBL25344636 | 0.88 | CASP1 (0.36) | CASP1FABP5BACE1FABP7EPHX2 | |
| SCHEMBL25968593 | 0.88 | L3MBTL1 (0.35) | CASP1ALDH1A1BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023154724-A2 | PROCESSES AND COMPOUNDS FOR PREPARING SPIROLIGOMERS | TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2023-08-17 | — | — | WO | disclosed |