Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.32 |
| ▸ | FABP7 | O15540 | 1/20 | 0.32 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.31 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25968518 | 0.94 | CASP1 (0.39) | CASP1EPHX2OPRD1BACE1FABP5 | |
| SCHEMBL25968525 | 0.91 | CASP1 (0.37) | CASP1EPHX2ALDH1A1BACE1FABP5 | |
| SCHEMBL25968601 | 0.90 | CASP1 (0.37) | CASP1EPHX2BACE1FABP5FABP7 | |
| SCHEMBL25344766 | 0.90 | CASP1 (0.37) | CASP1EPHX2BACE1FABP5FABP7 | |
| SCHEMBL25968589 | 0.89 | NAMPT (0.37) | CASP1EPHX2CYP3A4SMN1; SMN2TSHR | |
| SCHEMBL25968522 | 0.88 | SCN9A (0.43) | CASP1 | |
| SCHEMBL25968596 | 0.88 | CASP1 (0.36) | CASP1EPHX2BACE1FABP5FABP7 | |
| SCHEMBL25343338 | 0.88 | CASP1 (0.36) | CASP1EPHX2BACE1FABP5FABP7 | |
| SCHEMBL25344636 | 0.88 | CASP1 (0.36) | CASP1EPHX2OPRD1SMN1; SMN2TSHR | |
| SCHEMBL25968593 | 0.87 | L3MBTL1 (0.35) | CASP1L3MBTL1ALDH1A1CYP3A4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023154724-A2 | PROCESSES AND COMPOUNDS FOR PREPARING SPIROLIGOMERS | TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2023-08-17 | — | — | WO | disclosed |