Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25968407 | 0.88 | CASP1 (0.37) | CASP1 | |
| SCHEMBL25968400 | 0.84 | CASP1 (0.40) | CASP1 | |
| SCHEMBL25968518 | 0.84 | CASP1 (0.39) | CASP1OPRD1 | |
| SCHEMBL25968404 | 0.83 | CASP1 (0.37) | CASP1 | |
| SCHEMBL25345792 | 0.82 | CASP1 (0.37) | CASP1 | |
| SCHEMBL25968505 | 0.81 | CASP1 (0.37) | CASP1MAPTALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL25968601 | 0.80 | CASP1 (0.37) | CASP1 | |
| SCHEMBL25968525 | 0.80 | CASP1 (0.37) | CASP1ALDH1A1 | |
| SCHEMBL25344766 | 0.80 | CASP1 (0.37) | CASP1 | |
| SCHEMBL25968410 | 0.80 | CASP1 (0.36) | CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023154724-A2 | PROCESSES AND COMPOUNDS FOR PREPARING SPIROLIGOMERS | TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2023-08-17 | — | — | WO | disclosed |