Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 16/20 | 0.43 |
| ▸ | SCN5A | Q14524 | 10/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 9/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25968518 | 0.91 | CASP1 (0.39) | CASP1 | |
| SCHEMBL25968525 | 0.91 | CASP1 (0.37) | SCN9ASCN5AKCNH2CASP1 | |
| SCHEMBL25968519 | 0.88 | CASP1 (0.37) | CASP1 | |
| SCHEMBL25343338 | 0.88 | CASP1 (0.36) | CASP1 | |
| SCHEMBL25968596 | 0.88 | CASP1 (0.36) | CASP1 | |
| SCHEMBL25968601 | 0.88 | CASP1 (0.37) | CASP1 | |
| SCHEMBL25344766 | 0.88 | CASP1 (0.37) | CASP1 | |
| SCHEMBL25968589 | 0.87 | NAMPT (0.37) | CASP1HTT | |
| SCHEMBL25968598 | 0.86 | KDM4E (0.37) | SCN9ASCN5AKCNH2CASP1 | |
| SCHEMBL25968586 | 0.86 | ATM (0.43) | CASP1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023154724-A2 | PROCESSES AND COMPOUNDS FOR PREPARING SPIROLIGOMERS | TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2023-08-17 | — | — | WO | disclosed |