Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | FKBP1A | P62942 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | FPR1 | P21462 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | FNTA | P49354 | 1/20 | 0.33 |
| ▸ | FNTB | P49356 | 1/20 | 0.33 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.33 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.33 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25968518 | 0.92 | CASP1 (0.39) | CASP1 | |
| SCHEMBL25344766 | 0.91 | CASP1 (0.37) | NAMPTCASP1EPHX1CACNA1I | |
| SCHEMBL25968601 | 0.91 | CASP1 (0.37) | NAMPTCASP1EPHX1CACNA1I | |
| SCHEMBL25968525 | 0.87 | CASP1 (0.37) | CASP1FKBP1ASCN9A | |
| SCHEMBL25968598 | 0.87 | KDM4E (0.37) | NAMPTCASP1CYP3A4CYP2C19CYP1A2 | |
| SCHEMBL25968507 | 0.86 | CASP1 (0.36) | CASP1TDP1CACNA1GCACNA1HCACNA1I | |
| SCHEMBL25968519 | 0.86 | CASP1 (0.37) | CASP1CYP3A4SMN1; SMN2HSD17B10TDP1 | |
| SCHEMBL25968509 | 0.85 | CASP1 (0.36) | CASP1IDO1FNTAFNTB | |
| SCHEMBL25343338 | 0.85 | CASP1 (0.36) | CASP1 | |
| SCHEMBL25968596 | 0.85 | CASP1 (0.36) | CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023154724-A2 | PROCESSES AND COMPOUNDS FOR PREPARING SPIROLIGOMERS | TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2023-08-17 | — | — | WO | disclosed |