Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.48 |
| ▸ | LSS | P48449 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP4 | P49662 | 1/20 | 0.43 |
| ▸ | CASP5 | P51878 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24163320 | 0.88 | KDM4E (0.46) | HSD11B1ALDH1A1KDM4ETRPV6MEN1 | |
| SCHEMBL1143256 | 0.84 | SIGMAR1 (0.60) | HSD11B1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL28269086 | 0.79 | LSS (0.66) | HSD11B1ALDH1A1KDM4ETRPV6MEN1 | |
| SCHEMBL3453846 | 0.78 | ALDH1A1 (0.54) | HSD11B1ALDH1A1KDM4ESMN1; SMN2CYP2D6 | |
| SCHEMBL38659590 | 0.73 | KDM4E (0.58) | HSD11B1ALDH1A1KDM4ETRPV6MEN1 | |
| SCHEMBL3994683 | 0.72 | HRH3 (0.67) | ALDH1A1KDM4ELSSHPGDCASP1 | |
| SCHEMBL1667217 | 0.71 | ALDH1A1 (0.63) | ALDH1A1KDM4ETRPV6MEN1KMT2A | |
| SCHEMBL2056150 | 0.71 | MC4R (0.66) | ALDH1A1KDM4ELSSHPGDCASP1 | |
| SCHEMBL2208141 | 0.70 | HRH3 (0.71) | ALDH1A1KDM4EMEN1KMT2ALSS | |
| SCHEMBL13442 | 0.70 | HRH3 (0.71) | ALDH1A1KDM4EMEN1KMT2ALSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230257350-A1 | COMPOUNDS AND METHODS OF PROMOTING OLIGODENDROCYTE PRECURSOR DIFFERENTIATION | THE CLEVELAND CLINIC FOUNDATION | 2023-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230257350-A1 | COMPOUNDS AND METHODS OF PROMOTING OLIGODENDROCYTE PRECURSOR DIFFERENTIATION | CHAT, DCX, GAP43 | HSD11B1 2298/4885ALDH1A1 611/4885KDM4E 3073/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.