SCHEMBL25969246

SCHEMBL25969246

O=C1Cc2c(OCC3CCN(c4ccc(Br)cc4F)CC3)ccc(Cl)c2N1

nearest known ligand 0.43

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 7/20 0.39
SLC6A9 P48067 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20613102 0.90 TRPV4 (0.40) MGLLSLC6A9
SCHEMBL20612928 0.85 MGLL (0.43) MGLLSLC6A9
SCHEMBL20612908 0.82 MGLL (0.41) MGLL
SCHEMBL20597046 0.79 TRPV4 (0.32)
SCHEMBL20612870 0.78 MGLL (0.41) MGLLSLC6A9
SCHEMBL19301821 0.77 SLC6A9 (0.38) SLC6A9
SCHEMBL25969717 0.76 MGLL (0.44) MGLLSLC6A9
SCHEMBL25969805 0.76 MGLL (0.38) MGLLSLC6A9
SCHEMBL17543139 0.75 TRPV4 (0.34)
SCHEMBL25969706 0.75 MGLL (0.43) MGLLSLC6A9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3421454-B9 PIPERIDINE DERIVATIVE OTSUKA PHARMA CO LTD (JP) 2023-08-09 EP disclosed