Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | NPR3 | P17342 | 1/20 | 0.31 |
| ▸ | BTK | Q06187 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.30 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19328219 | 0.88 | GAA (0.36) | GAAEPHX1HTR2CSLC6A4HDAC4 | |
| SCHEMBL17493774 | 0.88 | GAA (0.36) | GAAEPHX1HTR2CSLC6A4HDAC4 | |
| SCHEMBL31407713 | 0.86 | BTK (0.35) | GAAEPHX1HTR2CSLC6A4BTK | |
| SCHEMBL25182328 | 0.86 | BTK (0.35) | GAAEPHX1HTR2CSLC6A4BTK | |
| SCHEMBL25980518 | 0.85 | GAA (0.38) | GAAEPHX1HTR2CSLC6A4HDAC4 | |
| SCHEMBL30878165 | 0.83 | THRB (0.38) | GAAEPHX1HTR2CSLC6A4HDAC4 | |
| SCHEMBL31407418 | 0.83 | BTK (0.38) | GAAEPHX1HTR2CSLC6A4BTK | |
| SCHEMBL25182277 | 0.83 | BTK (0.38) | GAAEPHX1HTR2CSLC6A4BTK | |
| SCHEMBL25969279 | 0.82 | GAA (0.33) | GAAEPHX1HTR2CSLC6A4 | |
| SCHEMBL8137775 | 0.79 | GAA (0.37) | GAAEPHX1HTR2CSLC6A4HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11718638-B2 | Compounds, compositions and methods for synthesis | WAVE LIFE SCIENCES LTD. (SG) | 2023-08-08 | — | — | US | disclosed |
| US-11718638-B2 | Compounds, compositions and methods for synthesis | WAVE LIFE SCIENCES LTD. (SG) | 2023-08-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11718638-B2 | Compounds, compositions and methods for synthesis | ALKBH1, DUT, RNGTT | GAA 624/4885EPHX1 2749/4885HTR2C 2469/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.