Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 14/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | STS | P08842 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2596938 | 0.82 | GPR119 (0.45) | FAAHGPR119STS | |
| SCHEMBL2596979 | 0.79 | TGFBR1 (0.41) | — | |
| SCHEMBL27988389 | 0.76 | KDM4E (0.51) | GPR119BACE1KDM4EPKMSTS | |
| SCHEMBL12725347 | 0.73 | GPR119 (0.45) | GPR119BACE1KDM4EPKM | |
| SCHEMBL26151149 | 0.73 | FPR2 (0.47) | FAAHGPR119BACE1KDM4EPKM | |
| SCHEMBL24791666 | 0.72 | KDM4E (0.48) | FAAHGPR119BACE1KDM4EPKM | |
| SCHEMBL16227969 | 0.72 | FPR2 (0.42) | FAAHGPR119BACE1KDM4EPKM | |
| SCHEMBL24791688 | 0.72 | KDM4E (0.48) | FAAHGPR119BACE1KDM4EPKM | |
| SCHEMBL16228344 | 0.71 | BACE1 (0.44) | FAAHGPR119BACE1KDM4EPKM | |
| SCHEMBL16227748 | 0.71 | KDM4E (0.44) | FAAHGPR119BACE1KDM4EPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011146287-A1 | PYRAZOLO[4,3-B]PYRIDINE-7-AMINE INHIBITORS OF ALK5 | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-11-24 | — | — | WO | disclosed |