SCHEMBL25973455

SCHEMBL25973455

Nc1c(-c2ccccc2)cncc1-c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDO2 P48775 2/20 0.48
LMNA P02545 2/20 0.48
ALDH1A1 P00352 2/20 0.48
HSD17B10 Q99714 2/20 0.48
PRKCZ Q05513 1/20 0.47
NPC1 O15118 2/20 0.44
RAB9A P51151 2/20 0.44
SMARCA2 P51531 1/20 0.43
SMARCA4 P51532 1/20 0.43
PBRM1 Q86U86 1/20 0.43
ADORA2A P29274 1/20 0.43
ADORA1 P30542 1/20 0.43
ATM Q13315 1/20 0.42
KDM4E B2RXH2 1/20 0.41
GLA P06280 1/20 0.41
HPGD P15428 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
PLK4 O00444 2/20 0.41
AURKA O14965 2/20 0.41
DAPK3 O43293 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22258410 0.89 ALDH1A1 (0.48) TDO2LMNAALDH1A1HSD17B10PRKCZ
SCHEMBL24499488 0.85 ALDH1A1 (0.45) TDO2LMNAALDH1A1HSD17B10PRKCZ
SCHEMBL1524405 0.85 CYP2A6 (0.45) TDO2LMNAALDH1A1HSD17B10PRKCZ
SCHEMBL5329333 0.80 ADORA2A (0.46) ALDH1A1HSD17B10NPC1RAB9AADORA2A
SCHEMBL27485032 0.79 CYP11B1 (0.45) TDO2LMNAPRKCZCYP3A4
SCHEMBL368306 0.78 IKBKB (0.49) ATMPLK4AURKADAPK3CHEK2
SCHEMBL24869112 0.76 ALDH1A1 (0.45) TDO2LMNAALDH1A1HSD17B10PRKCZ
SCHEMBL1822460 0.76 ALDH1A1 (0.62) TDO2LMNAALDH1A1HSD17B10SMARCA2
SCHEMBL23623516 0.75 ALDH1A1 (0.48) TDO2LMNAALDH1A1HSD17B10PRKCZ
SCHEMBL23729132 0.75 RPS6KA3 (0.42) TDO2LMNAALDH1A1HSD17B10PRKCZ

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230263057-A1 LIGHT-EMITTING DEVICE INCLUDING CONDENSED CYCLIC COMPOUND, ELECTRONIC APPARATUS INCLUDING THE SAME, AND THE CONDENSED CYCLIC COMPOUND SAMSUNG DISPLAY CO., LTD. (KR) 2023-08-17 US disclosed
US-20230263057-A1 LIGHT-EMITTING DEVICE INCLUDING CONDENSED CYCLIC COMPOUND, ELECTRONIC APPARATUS INCLUDING THE SAME, AND THE CONDENSED CYCLIC COMPOUND SAMSUNG DISPLAY CO., LTD. (KR) 2023-08-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230263057-A1 LIGHT-EMITTING DEVICE INCLUDING CONDENSED CYCLIC COMPOUND, ELECTRONIC APPARATUS INCLUDING THE SAME, AND THE CONDENSED CYCLIC COMPOUND CRY1, CCNE2, CRY2 TDO2 3904/4885LMNA 989/4885ALDH1A1 616/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.