Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 5/20 | 0.36 |
| ▸ | CA12 | O43570 | 4/20 | 0.36 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 4/20 | 0.36 |
| ▸ | VDR | P11473 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 4/20 | 0.35 |
| ▸ | CA7 | P43166 | 2/20 | 0.35 |
| ▸ | CA3 | P07451 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22262073 | 0.89 | STAT3 (0.34) | STAT3GAACA9CA12MMP2 | |
| SCHEMBL22262072 | 0.89 | STAT3 (0.34) | STAT3GAACA9CA12MMP2 | |
| SCHEMBL1030711 | 0.87 | CA12 (0.39) | STAT3GAACA9CA12MMP2 | |
| SCHEMBL12300749 | 0.86 | CA12 (0.38) | GAACA9CA12MMP2CA14 | |
| SCHEMBL1375594 | 0.86 | L3MBTL1 (0.43) | GAACA9CA12ALDH1A1MEN1 | |
| SCHEMBL8622516 | 0.85 | MMP2 (0.41) | STAT3GAACA9CA12MMP2 | |
| SCHEMBL259735 | 0.85 | STAT3 (0.36) | STAT3GAACA9CA12MMP2 | |
| SCHEMBL13992035 | 0.85 | STAT3 (0.36) | STAT3GAACA9CA12MMP2 | |
| SCHEMBL8871679 | 0.82 | STAT3 (0.43) | STAT3GAACA9CA12ALDH1A1 | |
| SCHEMBL139911 | 0.79 | CA12 (0.41) | STAT3GAACA9CA12ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111187325-A | Anti-tumor (4' R) -methyl- α -L-ribofuranose nucleoside and preparation method thereof | 郑州大学 | 2020-05-22 | — | — | CN | claimed |
| WO-2015051874-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF TENOFOVIR DISOPROXIL AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF | ZENTIVA, K.S. (CZ) | 2015-04-16 | — | — | WO | claimed |
| EP-2860185-A1 | An improved process for the preparation of Tenofovir disoproxil and pharmaceutically acceptable salts thereof | Zentiva, k.s. (CZ) | 2015-04-15 | — | — | EP | claimed |
| US-5733896-A | VIRICIDE FOR RETROVIRUS | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) | 1998-03-31 | — | — | US | claimed |
| CN-111187325-B | Antitumor (4' R) -methyl-alpha-L-ribofuranose nucleoside and preparation method thereof | 郑州大学 | 2022-09-02 | — | — | CN | disclosed |
| US-11292812-B2 | 3′3′-cyclic dinucleotides | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR, V.V.I. (CZ) | 2022-04-05 | — | — | US | disclosed |
| US-11149052-B2 | 2′3′-cyclic dinucleotides | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR, V.V.I. (CZ) | 2021-10-19 | — | — | US | disclosed |
| EP-3774832-A1 | 3'3'-CYCLIC DINUCLEOTIDES | Institute of Organic Chemistry and Biochemistry ASCR, V.V.I. (CZ) | 2021-02-17 | — | — | EP | disclosed |
| EP-3774831-A1 | 2'3'-CYCLIC DINUCLEOTIDES | Institute of Organic Chemistry and Biochemistry ASCR, V.V.I. (CZ) | 2021-02-17 | — | — | EP | disclosed |
| CN-111187325-A | Anti-tumor (4' R) -methyl- α -L-ribofuranose nucleoside and preparation method thereof | 郑州大学 | 2020-05-22 | — | — | CN | disclosed |
| CN-108586532-B | Preparation method of tenofovir disoproxil fumarate | 科兴生物制药股份有限公司 | 2020-05-08 | — | — | CN | disclosed |
| US-20190322695-A1 | 2'3'-CYCLIC DINUCLEOTIDES | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR,V.V.I. (CZ) | 2019-10-24 | — | — | US | disclosed |
| EP-0630381-A1 | ANTIVIRAL ACYCLIC PHOSPHONOMETHOXYALKYL SUBSTITUTED, ALKENYL AND ALKYNYL PURINE AND PYRIMIDINE DERIVATIVES. | ACAD OF SCIENCE CZECH REPUBLIC (CS) | 1994-12-28 | — | — | EP | disclosed |
| US-5302585-A | Viricides, HIV virus | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CS) | 1994-04-12 | — | — | US | disclosed |
| WO-1994003467-A2 | ANTIRETROVIRAL ENANTIOMERIC NUCLEOTIDE ANALOGS | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) | 1994-02-17 | — | — | WO | disclosed |
| EP-0550574-A1 | HETEROCYCLIC COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-07-14 | — | — | EP | disclosed |
| WO-1993007157-A1 | ANTIVIRAL ACYCLIC PHOSPHONOMETHOXYALKYL SUBSTITUTED, ALKENYL AND ALKYNYL PURINE AND PYRIMIDINE DERIVATIVES | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OFTHE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) | 1993-04-15 | — | — | WO | disclosed |
| WO-1992005180-A1 | HETEROCYCLIC COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1992-04-02 | — | — | WO | disclosed |
| EP-0454427-A1 | Antiretroviral bases | Institute of Organic Chemistry and Biochemistry of the Academy of Sciences of the Czech Republic (CZ) | 1991-10-30 | — | — | EP | disclosed |
| EP-0452935-A1 | Chiral 2-(phosphonomethoxy)propyl guanines as antiviral agents | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CS) | 1991-10-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11149052-B2 | 2′3′-cyclic dinucleotides | STING1, MAVS, CGAS | STAT3 1149/4885GAA 3558/4885CA9 4844/4885 |
| US-20190322695-A1 | 2'3'-CYCLIC DINUCLEOTIDES | STING1, MAVS, CGAS | STAT3 1297/4885GAA 3577/4885CA9 4848/4885 |
| US-11292812-B2 | 3′3′-cyclic dinucleotides | STING1, CGAS, MAVS | STAT3 1461/4885GAA 3693/4885CA9 4844/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.