SCHEMBL2597400

SCHEMBL2597400

CCCOC(=O)Oc1ccc([N+](=O)[O-])cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCL9 O00512 1/20 0.63
CTNNB1 P35222 1/20 0.63
HTR2A P28223 1/20 0.58
MGLL Q99685 2/20 0.56
GAA P10253 1/20 0.54
MAPT P10636 6/20 0.50
CRHBP P24387 1/20 0.49
CRHR2 Q13324 1/20 0.49
SMN1; SMN2 Q16637 4/20 0.48
MAPK1 P28482 3/20 0.48
LMNA P02545 3/20 0.48
MMP2 P08253 1/20 0.48
MMP9 P14780 1/20 0.48
MMP14 P50281 1/20 0.48
KMT2A Q03164 3/20 0.48
NPC1 O15118 2/20 0.48
RAB9A P51151 2/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
ALDH1A1 P00352 4/20 0.47
POLB P06746 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL30544551 0.98 BCL9 (0.61) BCL9CTNNB1HTR2AMGLLGAA
SCHEMBL1144551 0.92 MGLL (0.62) BCL9CTNNB1HTR2AMGLLGAA
SCHEMBL916518 0.91 BCL9 (0.57) BCL9CTNNB1HTR2AMGLLGAA
SCHEMBL30232973 0.91 BCL9 (0.57) BCL9CTNNB1HTR2AMGLLGAA
SCHEMBL27882785 0.91 MGLL (0.60) BCL9CTNNB1HTR2AMGLLGAA
SCHEMBL409598 0.90 HTR2A (0.59) BCL9CTNNB1HTR2AMGLLGAA
SCHEMBL1958366 0.90 MGLL (0.60) BCL9CTNNB1HTR2AMGLLGAA
SCHEMBL21433779 0.88 MGLL (0.62) BCL9CTNNB1HTR2AMGLLGAA
SCHEMBL21433828 0.88 MGLL (0.62) BCL9CTNNB1HTR2AMGLLGAA
SCHEMBL21777065 0.88 MGLL (0.62) BCL9CTNNB1HTR2AMGLLGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1313794-B1 ELASTOMERIC FUNCTIONAL BIODEGRADABLE COPOLYESTER AMIDES AND COPOLYESTER URETHANES CORNELL RES FOUNDATION INC (US) 2006-11-29 EP claimed
US-20040063606-A1 Elastomeric functional biodegradable copolyester amides and copolyester urethanes CORNELL RESEARCH FOUNDATION, INC. 2004-04-01 US claimed
EP-1313794-A2 ELASTOMERIC FUNCTIONAL BIODEGRADABLE COPOLYESTER AMIDES AND COPOLYESTER URETHANES CORNELL RESEARCH FOUNDATION, INC. (US) 2003-05-28 EP claimed
WO-2002018477-A2 ELASTOMERIC FUNCTIONAL BIODEGRADABLE COPOLYESTER AMIDES AND COPOLYESTER URETHANES CORNELL RESEARCH FOUNDATION, INC. (US) 2002-03-07 WO claimed
CN-122070276-A Prodrugs of xanomeline, prodrugs of trospium chloride and methods of using the same 人类生物科学股份有限公司 2026-05-19 CN disclosed
US-20250296912-A1 AFFINITY ILLUDOFULVENE CONJUGATES Illudent, Inc. (US) 2025-09-25 US disclosed
WO-2025094035-A1 TOLL-LIKE RECEPTOR AGONISTS AND CONJUGATES THEREOF PFIZER INC. (US) 2025-05-08 WO disclosed
US-12269793-B2 Affinity illudofulvene conjugates AF CHEMICALS, LLC (US) 2025-04-08 US disclosed
US-20230321267-A1 Method And Molecules THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2023-10-12 US disclosed
US-20230321267-A1 Method And Molecules THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2023-10-12 US disclosed
US-11759526-B2 Method and molecules MEDIMMUNE, LLC (US) 2023-09-19 US disclosed
US-11759526-B2 Method and molecules MEDIMMUNE, LLC (US) 2023-09-19 US disclosed
EP-1340753-B1 CARBAMATE DERIVATIVES, PROCESS FOR PRODUCING THE SAME AND USE THEREOF TAKEDA PHARMACEUTICAL (JP) 2006-01-11 EP disclosed
EP-1411933-A1 ALPHA-KETOAMIDE DERIVATIVES AS CATHEPSIN K INHIBITORS SmithKline Beecham Corporation (US) 2004-04-28 EP disclosed
US-20040063606-A1 Elastomeric functional biodegradable copolyester amides and copolyester urethanes CORNELL RESEARCH FOUNDATION, INC. 2004-04-01 US disclosed
US-20040038986-A1 Carbamate derivatives, process for producing the same and use thereof TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2004-02-26 US disclosed
EP-1340753-A1 CARBAMATE DERIVATIVES, PROCESS FOR PRODUCING THE SAME AND USE THEREOF Takeda Chemical Industries, Ltd. (JP) 2003-09-03 EP disclosed
EP-1313794-A2 ELASTOMERIC FUNCTIONAL BIODEGRADABLE COPOLYESTER AMIDES AND COPOLYESTER URETHANES CORNELL RESEARCH FOUNDATION, INC. (US) 2003-05-28 EP disclosed
WO-2003013518-A1 ALPHA-KETOAMIDE DERIVATIVES AS CATHEPSIN K INHIBITORS SMITHKLINE BEECHAM CORPORATION (US) 2003-02-20 WO disclosed
WO-2002018477-A2 ELASTOMERIC FUNCTIONAL BIODEGRADABLE COPOLYESTER AMIDES AND COPOLYESTER URETHANES CORNELL RESEARCH FOUNDATION, INC. (US) 2002-03-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250296912-A1 AFFINITY ILLUDOFULVENE CONJUGATES OGFR, TNFSF11, FCER2 BCL9 2641/4885CTNNB1 3716/4885HTR2A 2731/4885
US-20230321267-A1 Method And Molecules PAICS, EPCAM, SQLE BCL9 1174/4885CTNNB1 3192/4885HTR2A 3277/4885
US-20040038986-A1 Carbamate derivatives, process for producing the same and use thereof CFH, F11, F2 BCL9 1235/4885CTNNB1 2713/4885HTR2A 3862/4885
US-11759526-B2 Method and molecules PAICS, EPCAM, SQLE BCL9 1174/4885CTNNB1 3192/4885HTR2A 3277/4885
US-12269793-B2 Affinity illudofulvene conjugates OGFR, TNFSF11, FCER2 BCL9 2641/4885CTNNB1 3716/4885HTR2A 2731/4885
US-20040063606-A1 Elastomeric functional biodegradable copolyester amides and copolyester urethanes PUF60, UROD, UBE2I BCL9 4755/4885CTNNB1 4778/4885HTR2A 3096/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.