SCHEMBL916518

SCHEMBL916518

CCCOCCOCCOCCOC(=O)Oc1ccc([N+](=O)[O-])cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCL9 O00512 1/20 0.57
CTNNB1 P35222 1/20 0.57
HTR2A P28223 1/20 0.53
MGLL Q99685 2/20 0.51
GAA P10253 1/20 0.49
MAPT P10636 5/20 0.46
CRHBP P24387 1/20 0.45
CRHR2 Q13324 1/20 0.45
SMN1; SMN2 Q16637 4/20 0.44
KMT2A Q03164 3/20 0.44
NPC1 O15118 2/20 0.44
RAB9A P51151 2/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
ALDH1A1 P00352 4/20 0.43
TDP1 Q9NUW8 1/20 0.43
LMNA P02545 3/20 0.43
MEN1 O00255 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
MAPK1 P28482 3/20 0.43
CYP3A4 P08684 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30232973 1.00 BCL9 (0.57) BCL9CTNNB1HTR2AMGLLGAA
SCHEMBL125510 0.93 HTR2A (0.56) BCL9CTNNB1HTR2AMGLLGAA
SCHEMBL10062010 0.93 HTR2A (0.56) BCL9CTNNB1HTR2AMGLLGAA
SCHEMBL2597400 0.91 BCL9 (0.63) BCL9CTNNB1HTR2AMGLLGAA
SCHEMBL18699060 0.90 BCL9 (0.55) BCL9CTNNB1HTR2AMGLLGAA
Hydrochloric Acid SCHEMBL30544551 0.90 BCL9 (0.61) BCL9CTNNB1HTR2AMGLLGAA
SCHEMBL23044637 0.89 HTR2A (0.53) BCL9CTNNB1HTR2AMGLLGAA
SCHEMBL1104745 0.89 HTR2A (0.53) BCL9CTNNB1HTR2AMGLLGAA
SCHEMBL12082016 0.89 HTR2A (0.53) BCL9CTNNB1HTR2AMGLLGAA
SCHEMBL30233044 0.89 HTR2A (0.53) BCL9CTNNB1HTR2AMGLLGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105801686-B Insulin-oligomer conjugates, formulations and uses thereof 比奥孔有限公司 2020-04-07 CN disclosed
EP-2626368-B1 Insulin-oligomer conjugates, formulations and uses thereof BIOCON LTD (IN) 2016-12-21 EP disclosed
US-9101596-B2 Cation complexes of insulin compound conjugates, formulations and uses thereof BIOCON LIMITED (IN) 2015-08-11 US disclosed
US-9102758-B2 Insulin-oligomer conjugates, formulations and uses thereof BIOCON LIMITED (IN) 2015-08-11 US disclosed
US-9101596-B2 Cation complexes of insulin compound conjugates, formulations and uses thereof BIOCON LIMITED (IN) 2015-08-11 US disclosed
US-9102758-B2 Insulin-oligomer conjugates, formulations and uses thereof BIOCON LIMITED (IN) 2015-08-11 US disclosed
US-9102758-B2 Insulin-oligomer conjugates, formulations and uses thereof BIOCON LIMITED (IN) 2015-08-11 US disclosed
US-9101596-B2 Cation complexes of insulin compound conjugates, formulations and uses thereof BIOCON LIMITED (IN) 2015-08-11 US disclosed
EP-1773878-B1 INSULIN-OLIGOMER CONJUGATES, FORMULATIONS AND USES THEREOF BIOCON LTD (IN) 2015-03-04 EP disclosed
US-8563685-B2 Fatty acid formulations and oral delivery of proteins and peptides, and uses thereof BIOCON LIMITED (IN) 2013-10-22 US disclosed
US-20100105605-A1 FATTY ACID FORMULATIONS AND ORAL DELIVERY OF PROTEINS AND PEPTIDES, AND USES THEREOF RADHAKRISHNAN BALASINGAM 2010-04-29 US disclosed
US-20100105605-A1 FATTY ACID FORMULATIONS AND ORAL DELIVERY OF PROTEINS AND PEPTIDES, AND USES THEREOF RADHAKRISHNAN BALASINGAM 2010-04-29 US disclosed
US-7605123-B2 Fatty acid formulations for oral delivery of proteins and peptides, and uses thereof BIOCON LTD. (IN) 2009-10-20 US disclosed
US-7605123-B2 Fatty acid formulations for oral delivery of proteins and peptides, and uses thereof BIOCON LTD. (IN) 2009-10-20 US disclosed
US-7605123-B2 Fatty acid formulations for oral delivery of proteins and peptides, and uses thereof BIOCON LTD. (IN) 2009-10-20 US disclosed
EP-1773878-A2 INSULIN-OLIGOMER CONJUGATES, FORMULATIONS AND USES THEREOF Nobex Corporation (US) 2007-04-18 EP disclosed
WO-2006014673-A2 INSULIN-OLIGOMER CONJUGATES, FORMULATIONS AND USES THEREOF NOBEX CORPORATION (US) 2006-02-09 WO disclosed
US-20060019873-A1 Cation complexes of insulin compound conjugates, formulations and uses thereof BIOCON LIMITED (IN) 2006-01-26 US disclosed
US-20060019874-A1 Cation complexes of insulin compund conjugates, formulation and uses thereof NOBEX CORPORATION 2006-01-26 US disclosed
US-20060018874-A1 Fatty acid formulations for oral delivery of proteins and peptides, and uses thereof BIOCON LIMITED (IN) 2006-01-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060019873-A1 Cation complexes of insulin compound conjugates, formulations and uses thereof GPR119, INSR, IAPP BCL9 4443/4885CTNNB1 4357/4885HTR2A 3089/4885
US-20100105605-A1 FATTY ACID FORMULATIONS AND ORAL DELIVERY OF PROTEINS AND PEPTIDES, AND USES THEREOF FABP2, SLC27A1, SLC27A2 BCL9 817/4885CTNNB1 4561/4885HTR2A 3254/4885
US-20060018874-A1 Fatty acid formulations for oral delivery of proteins and peptides, and uses thereof FABP2, SLC27A1, SLC27A2 BCL9 844/4885CTNNB1 4581/4885HTR2A 3259/4885
US-20060019874-A1 Cation complexes of insulin compund conjugates, formulation and uses thereof INSR, GPR119, IAPP BCL9 3751/4885CTNNB1 4883/4885HTR2A 4053/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.