Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.60 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.58 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.58 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.58 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.58 |
| ▸ | HTR1D | P28221 | 1/20 | 0.58 |
| ▸ | HTR1B | P28222 | 1/20 | 0.58 |
| ▸ | HTR2B | P41595 | 1/20 | 0.58 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.58 |
| ▸ | SMOX | Q9NWM0 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 6/20 | 0.58 |
| ▸ | HPGD | P15428 | 6/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25974169 | 0.96 | OPRK1 (0.61) | KDM4EALDH1A1OPRK1PAOXADRA2A | |
| SCHEMBL25974223 | 0.89 | TP53 (0.53) | KDM4EALDH1A1OPRK1PAOXADRA2A | |
| SCHEMBL25974195 | 0.85 | OPRK1 (0.58) | KDM4EALDH1A1OPRK1PAOXADRA2A | |
| SCHEMBL25970334 | 0.82 | OPRK1 (0.66) | KDM4EALDH1A1OPRK1PAOXADRA2A | |
| SCHEMBL25970464 | 0.81 | OPRK1 (0.62) | KDM4EALDH1A1OPRK1PAOXADRA2A | |
| SCHEMBL25970331 | 0.81 | OPRK1 (0.68) | KDM4EALDH1A1OPRK1PAOXADRA2A | |
| Hydrochloric Acid SCHEMBL30516229 | 0.81 | OPRK1 (0.64) | KDM4EALDH1A1OPRK1PAOXADRA2A | |
| SCHEMBL1719216 | 0.81 | OPRK1 (0.64) | KDM4EALDH1A1OPRK1PAOXADRA2A | |
| SCHEMBL25969026 | 0.81 | OPRK1 (0.67) | KDM4EALDH1A1OPRK1PAOXADRA2A | |
| SCHEMBL25970233 | 0.80 | OPRK1 (0.69) | KDM4EALDH1A1OPRK1PAOXADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250161307-A1 | PYRAZOLOPYRIMIDINES AS MODULATORS OF SPERMINE OXIDASE | JANSSEN PHARMACEUTICA NV (BE) | 2025-05-22 | — | — | US | disclosed |
| WO-2023141866-A1 | PYRAZOLOPYRIMIDINES AS MODULATORS OF SPERMINE OXIDASE | JANSSEN PHARMACEUTICA NV (BE) | 2023-08-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250161307-A1 | PYRAZOLOPYRIMIDINES AS MODULATORS OF SPERMINE OXIDASE | SMOX, SRM, SMS | KDM4E 1480/4885ALDH1A1 160/4885OPRK1 2700/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.