Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25975148 | 0.88 | NPC1 (0.36) | PDE10ANPC1CASP3RAB9ASENP8 | |
| SCHEMBL30519319 | 0.84 | PTGS2 (0.35) | PDE10ANPC1CASP3RAB9ASENP8 | |
| SCHEMBL25343113 | 0.84 | PTGS2 (0.35) | PDE10ANPC1CASP3RAB9ASENP8 | |
| SCHEMBL25973972 | 0.80 | TRPV1 (0.39) | PDE10ANPC1CASP3RAB9ASENP8 | |
| SCHEMBL30519411 | 0.80 | KCNH2 (0.38) | PDE10ARAB9ATRPV1MAPTATM | |
| SCHEMBL25340813 | 0.80 | KCNH2 (0.38) | PDE10ARAB9ATRPV1MAPTATM | |
| SCHEMBL25973903 | 0.79 | NPC1 (0.39) | NPC1CASP3RAB9ASENP8SENP7 | |
| SCHEMBL30519311 | 0.75 | SLC6A2 (0.36) | PDE10ANPC1CASP3RAB9ASENP8 | |
| SCHEMBL25341461 | 0.75 | SLC6A2 (0.36) | PDE10ANPC1CASP3RAB9ASENP8 | |
| SCHEMBL25375442 | 0.75 | FEN1 (0.38) | RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146513-A1 | COMPOUNDS AND METHODS OF USE THEREOF | VIVACE THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |