Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPR | P35270 | 3/20 | 0.42 |
| ▸ | GUCY1A1 | Q02108 | 3/20 | 0.33 |
| ▸ | GUCY1B1 | Q02153 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CCR2 | P41597 | 1/20 | 0.32 |
| ▸ | CCR5 | P51681 | 1/20 | 0.32 |
| ▸ | HTR3A | P46098 | 4/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.32 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | PDE5A | O76074 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | METAP2 | P50579 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25974820 | 0.90 | SPR (0.42) | SPRGUCY1A1GUCY1B1L3MBTL1CCR2 | |
| SCHEMBL19158836 | 0.89 | SPR (0.42) | SPRGUCY1A1GUCY1B1L3MBTL1CCR2 | |
| SCHEMBL19264146 | 0.75 | L3MBTL1 (0.46) | SPRL3MBTL1PDE10APDE5A | |
| SCHEMBL19264342 | 0.74 | L3MBTL1 (0.42) | SPRL3MBTL1PDE5ACYP1A2 | |
| SCHEMBL326986 | 0.73 | GUCY1A1 (0.38) | GUCY1A1GUCY1B1HTR3APDE5A | |
| SCHEMBL16167735 | 0.73 | SPR (0.52) | SPRCCR2CCR5ADORA2AADORA2B | |
| SCHEMBL19264147 | 0.71 | SPR (0.38) | SPRL3MBTL1ADORA2AADORA2BPDE5A | |
| SCHEMBL25975320 | 0.71 | GUCY1A1 (0.41) | SPRGUCY1A1GUCY1B1HTR3A | |
| SCHEMBL25975200 | 0.70 | GUCY1A1 (0.53) | GUCY1A1GUCY1B1PDE5A | |
| SCHEMBL25975201 | 0.70 | GUCY1A1 (0.53) | GUCY1A1GUCY1B1PDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230257398-A1 | PYRIMIDINE-BASED TRICYCLIC COMPOUND AND USE THEREOF | CHIA TAL TIANQING PHARMACEUTICAL GROUP CO., LTD. (CN) | 2023-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230257398-A1 | PYRIMIDINE-BASED TRICYCLIC COMPOUND AND USE THEREOF | TYMP, TYMS, DPYD | SPR 1566/4885GUCY1A1 2940/4885GUCY1B1 2239/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.