Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALPI | P09923 | 1/20 | 0.42 |
| ▸ | ALPG | P10696 | 1/20 | 0.42 |
| ▸ | PLAA | Q9Y263 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | DUT | P33316 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25976177 | 0.86 | ALPI (0.48) | SMN1; SMN2LMNAHTTGAAKMT2A | |
| SCHEMBL19087047 | 0.83 | HTT (0.60) | SMN1; SMN2LMNAHTTGAAKMT2A | |
| SCHEMBL10175541 | 0.77 | LMNA (0.54) | SMN1; SMN2LMNAHTTGAAKMT2A | |
| SCHEMBL6937303 | 0.77 | LMNA (0.54) | SMN1; SMN2LMNAHTTGAAKMT2A | |
| SCHEMBL18534152 | 0.76 | LMNA (0.53) | SMN1; SMN2LMNAHTTGAAKMT2A | |
| SCHEMBL31124644 | 0.76 | LMNA (0.47) | SMN1; SMN2LMNAHTTGAAKMT2A | |
| SCHEMBL19087158 | 0.76 | SMN1; SMN2 (0.52) | SMN1; SMN2LMNAHTTGAAKMT2A | |
| Hydrochloric Acid SCHEMBL28842191 | 0.76 | LMNA (0.52) | SMN1; SMN2LMNAHTTGAAKMT2A | |
| SCHEMBL19087087 | 0.74 | L3MBTL1 (0.56) | SMN1; SMN2LMNAHTTGAAKMT2A | |
| SCHEMBL26085647 | 0.74 | LMNA (0.55) | SMN1; SMN2LMNAHTTGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023154282-A1 | COMPOUNDS HAVING A T-STRUCTURE FORMED BY AT LEAST FOUR CYCLES FOR USE IN THE TREATMENT OF CANCER AND OTHER INDICATIONS | THERAS, INC. (US) | 2023-08-17 | — | — | WO | disclosed |