Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | PADI1 | Q9ULC6 | 1/20 | 0.36 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ANPEP | P15144 | 1/20 | 0.35 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HRH2 | P25021 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8693562 | 0.76 | CHRM5 (0.38) | CHRM5CHRM3SMN1; SMN2SIGMAR1 | |
| SCHEMBL19156830 | 0.74 | FAAH (0.45) | CHRM5CHRM3SIGMAR1ALDH1A1HRH2 | |
| SCHEMBL8693568 | 0.72 | MEN1 (0.42) | MEN1KMT2ASMN1; SMN2SIGMAR1ALDH1A1 | |
| SCHEMBL6603994 | 0.71 | CHRM5 (0.44) | CHRM5CHRM3MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9801548 | 0.70 | SMN1; SMN2 (0.46) | CHRM5CHRM3MEN1KMT2APADI1 | |
| SCHEMBL22320733 | 0.70 | SMN1; SMN2 (0.46) | CHRM5CHRM3MEN1KMT2APADI1 | |
| SCHEMBL27438939 | 0.70 | CHRM5 (0.46) | CHRM5CHRM3MEN1KMT2APADI1 | |
| SCHEMBL561818 | 0.70 | HRH2 (0.44) | MEN1KMT2ASMN1; SMN2ALDH1A1HRH2 | |
| Alcohol SCHEMBL7951329 | 0.70 | SMN1; SMN2 (0.37) | CHRM5CHRM3MEN1KMT2APADI1 | |
| SCHEMBL19443244 | 0.69 | FAAH (0.42) | CHRM5CHRM3HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3047274-A2 | PSA ENZYMATIC ACTIVITY: A NEW BIOMARKER FOR ASSESSING PROSTATE CANCER AGGRESSIVENESS | Ohmx Corporation (US) | 2016-07-27 | — | — | EP | disclosed |
| WO-2015042493-A2 | PSA ENZYMATIC ACTIVITY: A NEW BIOMARKER FOR ASSESSING PROSTATE CANCER AGGRESSIVENESS | OHMX CORPORATION (US) | 2015-03-26 | — | — | WO | disclosed |
| EP-2571997-A2 | ENZYMATIC ACTIVITY OF PSA AS DIAGNOSTIC MARKER FOR PROSTATE CANCER | Ohmx Corporation (US) | 2013-03-27 | — | — | EP | disclosed |
| WO-2011146143-A2 | DETECTION OF CANCER BY ASSAYING PSA ENZYMATIC ACTIVITY | OHMX CORPORATION (US) | 2011-11-24 | — | — | WO | disclosed |