SCHEMBL2597712

SCHEMBL2597712

CCC(NCC(=O)O)N1CCNCC1C

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 1/20 0.32
OPRD1 P41143 2/20 0.32
PLD1 Q13393 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL561819 0.77 OPRD1 (0.39) OPRD1
SCHEMBL6039530 0.75
SCHEMBL1128450 0.75 DPP4 (0.35) DPP4OPRD1
SCHEMBL665675 0.71 LMNA (0.40) DPP4
SCHEMBL28867215 0.71 DPP4 (0.33) DPP4
SCHEMBL6492461 0.71 DPP4 (0.33) DPP4
SCHEMBL3097851 0.69 TDP1 (0.33) DPP4
SCHEMBL27841751 0.69 DPP4 (0.39) DPP4PLD1
SCHEMBL27841744 0.69 DPP4 (0.39) DPP4PLD1
SCHEMBL9092111 0.69 SLC6A3 (0.35) DPP4OPRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3047274-A2 PSA ENZYMATIC ACTIVITY: A NEW BIOMARKER FOR ASSESSING PROSTATE CANCER AGGRESSIVENESS Ohmx Corporation (US) 2016-07-27 EP disclosed
WO-2015042493-A2 PSA ENZYMATIC ACTIVITY: A NEW BIOMARKER FOR ASSESSING PROSTATE CANCER AGGRESSIVENESS OHMX CORPORATION (US) 2015-03-26 WO disclosed
EP-2571997-A2 ENZYMATIC ACTIVITY OF PSA AS DIAGNOSTIC MARKER FOR PROSTATE CANCER Ohmx Corporation (US) 2013-03-27 EP disclosed
WO-2011146143-A2 DETECTION OF CANCER BY ASSAYING PSA ENZYMATIC ACTIVITY OHMX CORPORATION (US) 2011-11-24 WO disclosed