Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | CPN1 | P15169 | 1/20 | 0.30 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
| ▸ | BRD1 | O95696 | 1/20 | 0.30 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL665675 | 0.86 | LMNA (0.40) | DPP4 | |
| SCHEMBL10685011 | 0.77 | SIGMAR1 (0.37) | SIGMAR1 | |
| SCHEMBL28867215 | 0.76 | DPP4 (0.33) | DPP4 | |
| SCHEMBL6492461 | 0.76 | DPP4 (0.33) | DPP4HTR2C | |
| SCHEMBL29091269 | 0.75 | RAB9A (0.38) | DPP4HTR2CKDM4E | |
| SCHEMBL2597712 | 0.75 | DPP4 (0.32) | DPP4OPRD1 | |
| SCHEMBL27841751 | 0.74 | DPP4 (0.39) | DPP4HTR2CKDM4ESIGMAR1 | |
| SCHEMBL27841744 | 0.74 | DPP4 (0.39) | DPP4HTR2CKDM4ESIGMAR1 | |
| SCHEMBL3097851 | 0.74 | TDP1 (0.33) | DPP4HTR2C | |
| SCHEMBL16315840 | 0.73 | SLC6A9 (0.45) | DPP4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2282724-A2 | MODIFIED DRUGS FOR USE IN LIPOSOMAL NANOPARTICLES | The University Of British Columbia (CA) | 2011-02-16 | — | — | EP | disclosed |
| WO-2009141738-A2 | MODIFIED DRUGS FOR USE IN LIPOSOMAL NANOPARTICLES | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2009-11-26 | — | — | WO | disclosed |