Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 3/20 | 0.32 |
| ▸ | CES1 | P23141 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 5/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.31 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.30 |
| ▸ | PPARG | P37231 | 6/20 | 0.30 |
| ▸ | PPARD | Q03181 | 6/20 | 0.30 |
| ▸ | PPARA | Q07869 | 6/20 | 0.30 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | TLR2 | O60603 | 2/20 | 0.30 |
| ▸ | FABP4 | P15090 | 2/20 | 0.30 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.30 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8466765 | 1.00 | TDP1 (0.41) | TDP1HSD17B10PAOXCES2CES1 | |
| SCHEMBL4797472 | 1.00 | TDP1 (0.41) | TDP1HSD17B10PAOXCES2CES1 | |
| SCHEMBL27605472 | 1.00 | TDP1 (0.41) | TDP1HSD17B10PAOXCES2CES1 | |
| SCHEMBL7116355 | 0.96 | HSD17B10 (0.44) | TDP1HSD17B10PAOXBTN3A1 | |
| SCHEMBL27383510 | 0.92 | HSD17B10 (0.41) | TDP1HSD17B10BTN3A1 | |
| SCHEMBL11399369 | 0.88 | — | — | |
| SCHEMBL22986932 | 0.87 | CES2 (0.50) | TDP1HSD17B10CES2CES1TSHR | |
| SCHEMBL3461175 | 0.87 | HSD17B10 (0.33) | TDP1HSD17B10 | |
| SCHEMBL466592 | 0.87 | GPR84 (0.43) | TDP1HSD17B10TSHRLMNAGPR84 | |
| SCHEMBL3188281 | 0.87 | CES2 (0.50) | TDP1HSD17B10CES2CES1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230331803-A1 | CO-AGONISTS OF THE GLP-1 AND AMYLIN RECEPTORS | NOVO NORDISK A/S (DK) | 2023-10-19 | — | — | US | disclosed |
| EP-3788063-B1 | GIP DERIVATIVES AND USES THEREOF | NOVO NORDISK AS (DK) | 2023-08-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230331803-A1 | CO-AGONISTS OF THE GLP-1 AND AMYLIN RECEPTORS | GLP1R, GIPR, GCGR | TDP1 3262/4885HSD17B10 1800/4885PAOX 1219/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.