SCHEMBL4797472

SCHEMBL4797472

C=C(C)CCCCCC(=C)C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.41
HSD17B10 Q99714 2/20 0.41
PAOX Q6QHF9 1/20 0.35
CES2 O00748 3/20 0.32
CES1 P23141 3/20 0.32
TSHR P16473 5/20 0.32
LMNA P02545 1/20 0.32
NFKB1 P19838 1/20 0.32
PMP22 Q01453 1/20 0.32
BTN3A1 O00481 1/20 0.31
GPR84 Q9NQS5 7/20 0.30
PPARG P37231 6/20 0.30
PPARD Q03181 6/20 0.30
PPARA Q07869 6/20 0.30
HDAC11 Q96DB2 5/20 0.30
ALDH1A1 P00352 2/20 0.30
TLR2 O60603 2/20 0.30
FABP4 P15090 2/20 0.30
PTPN1 P18031 2/20 0.30
SLC22A6 Q4U2R8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8466765 1.00 TDP1 (0.41) TDP1HSD17B10PAOXCES2CES1
SCHEMBL25978438 1.00 TDP1 (0.41) TDP1HSD17B10PAOXCES2CES1
SCHEMBL27605472 1.00 TDP1 (0.41) TDP1HSD17B10PAOXCES2CES1
SCHEMBL7116355 0.96 HSD17B10 (0.44) TDP1HSD17B10PAOXBTN3A1
SCHEMBL27383510 0.92 HSD17B10 (0.41) TDP1HSD17B10BTN3A1
SCHEMBL11399369 0.88
SCHEMBL22986932 0.87 CES2 (0.50) TDP1HSD17B10CES2CES1TSHR
SCHEMBL3461175 0.87 HSD17B10 (0.33) TDP1HSD17B10
SCHEMBL466592 0.87 GPR84 (0.43) TDP1HSD17B10TSHRLMNAGPR84
SCHEMBL3188281 0.87 CES2 (0.50) TDP1HSD17B10CES2CES1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020058017-A1 Hair cosmetic compositions KAO CORPORATION (JP) 2002-05-16 US claimed
EP-1190696-A2 Hair cosmetic compositions and use thereof Kao Corporation (JP) 2002-03-27 EP claimed
US-5073666-A Hydrocarbon synthesis from lower alkanes at advanced temperatures and high pressures CORNELL RESEARCH FOUNDATION, INC. (US) 1991-12-17 US claimed
CN-111423403-B Isopentene flavonoid compound in daphne giraldii nitsche and application thereof 沈阳药科大学 2021-07-23 CN disclosed
WO-2008024426-A2 NANOSILVER-CONTAINING ABSORBENT ARTICLES NEUWIRTH ROBERT S (US) 2008-02-28 WO disclosed
US-7220800-B2 Water soluble contact lens blocking composition with absorbent disintegrant ADHERENT LABORATORIES, INC. (US) 2007-05-22 US disclosed
US-20050234168-A1 Water soluble contact lens blocking composition with absorbent disintegrant ADHERENT LABORATORIES, INC. 2005-10-20 US disclosed
US-6280877-B1 DEHYDRATED LIQUID ABSORBING CROSSLINKED POLYMER PARTICLES, MIXING WITH ELECTROCHEMICAL ACTIVE MATERIAL EVEREADY BATTERY COMPANY, INC. 2001-08-28 US disclosed
US-20010003025-A1 Selecting dehydrated liquid absorbing cross-linked polymer particles, mixing an electrochemically active material, an electrolyte and selected crosslinked polymer particles, after absorbing electrolyte the size of partices are increased URRY LEWIS FREDERICK (US) 2001-06-07 US disclosed
EP-1078405-A1 METHOD FOR PRODUCING AN ELECTRODE CONTAINING ELECTROLYTE-ABSORBED POLYMER PARTICLES Eveready Battery Company, Inc. (US) 2001-02-28 EP disclosed
WO-1999057771-A1 METHOD FOR PRODUCING AN ELECTRODE CONTAINING ELECTROLYTE-ABSORBED POLYMER PARTICLES EVEREADY BATTERY COMPANY, INC. (US) 1999-11-11 WO disclosed
US-5073666-A Hydrocarbon synthesis from lower alkanes at advanced temperatures and high pressures CORNELL RESEARCH FOUNDATION, INC. (US) 1991-12-17 US disclosed
US-4235237-A Absorbent open network structure JOHNSON & JOHNSON (US) 1980-11-25 US disclosed
US-4102340-A Disposable article with particulate hydrophilic polymer in an absorbent bed JOHNSON & JOHNSON (US) 1978-07-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020058017-A1 Hair cosmetic compositions FHIT, MITF, HNMT TDP1 4364/4885HSD17B10 860/4885PAOX 551/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.