Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 5/20 | 0.34 |
| ▸ | NPC1 | O15118 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MIF | P14174 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2325299 | 0.77 | ALDH1A1 (0.50) | ALDH1A1KMT2AMEN1RAB9ANPC1 | |
| SCHEMBL29401847 | 0.76 | ALDH1A1 (0.49) | ALDH1A1KMT2AMEN1RAB9ANPC1 | |
| SCHEMBL25978764 | 0.75 | ALDH1A1 (0.56) | ALDH1A1KMT2AMEN1TSHRRAB9A | |
| SCHEMBL18988723 | 0.72 | ALDH1A1 (0.66) | ALDH1A1KMT2AMEN1TSHRRAB9A | |
| SCHEMBL20583517 | 0.71 | KMT2A (0.54) | ALDH1A1KMT2AMEN1RAB9ANPC1 | |
| SCHEMBL20583542 | 0.71 | ALDH1A1 (0.57) | ALDH1A1KMT2AMEN1RAB9ANPC1 | |
| SCHEMBL28647743 | 0.70 | ALDH1A1 (0.47) | ALDH1A1KMT2AMEN1RAB9ANPC1 | |
| SCHEMBL20533552 | 0.70 | ALDH1A1 (0.56) | ALDH1A1KMT2AMEN1RAB9ANPC1 | |
| SCHEMBL573354 | 0.70 | ALDH1A1 (0.63) | ALDH1A1KMT2ARAB9AKDM4EMIF | |
| SCHEMBL272269 | 0.70 | ALDH1A1 (0.63) | ALDH1A1KMT2AMEN1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250145599-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | MRJA THERAPEUTICS, INC. | 2025-05-08 | — | — | US | disclosed |
| WO-2023150663-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | RETUNE PHARMA INC. (US) | 2023-08-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250145599-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | IGF1R, IGFBP1, IGFBP2 | ALDH1A1 826/4885KMT2A 3829/4885BRD4 1097/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.