Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 2/20 | 0.47 |
| ▸ | HTR2C | P28335 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 5/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL25342537 | 0.99 | APLNR (0.49) | APLNRHTR2AHTR2CTSHRCYP1A2 | |
| SCHEMBL25980752 | 0.88 | APLNR (0.44) | APLNRHTR2AHTR2CTSHRCYP1A2 | |
| Hydrochloric Acid SCHEMBL30479625 | 0.87 | APLNR (0.44) | APLNRHTR2AHTR2CTSHRCYP1A2 | |
| Hydrochloric Acid SCHEMBL25342899 | 0.87 | APLNR (0.44) | APLNRHTR2AHTR2CTSHRCYP1A2 | |
| SCHEMBL25980671 | 0.81 | GAA (0.40) | APLNRHTR2AHTR2CTSHRCYP1A2 | |
| SCHEMBL25345233 | 0.77 | POLB (0.43) | TSHRKDM4CLMNAALDH1A1 | |
| SCHEMBL25341754 | 0.77 | APLNR (0.63) | APLNRHTR2AHTR2CHDAC3HDAC1 | |
| SCHEMBL25980674 | 0.75 | GAA (0.39) | TSHRKDM4CLMNAALDH1A1 | |
| SCHEMBL783785 | 0.70 | APLNR (1.00) | APLNRHTR2AHTR2CTSHRALDH1A1 | |
| SCHEMBL15969133 | 0.70 | APLNR (0.73) | APLNRHTR2AHTR2CTSHRHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023148501-A1 | HETEROCYCLIC DERIVATIVES AS MALT1 INHIBITORS | C4X DISCOVERY LIMITED (GB) | 2023-08-10 | — | — | WO | disclosed |