Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | DHFR | P00374 | 1/20 | 0.36 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | APLNR | P35414 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25345233 | 0.85 | POLB (0.43) | GAAALDH1A1KDM4ETDP1KMT2A | |
| SCHEMBL25980674 | 0.82 | GAA (0.39) | GAAALDH1A1KDM4ETDP1KMT2A | |
| SCHEMBL25980680 | 0.81 | APLNR (0.50) | ALDH1A1LMNAAPLNRHTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL25342537 | 0.80 | APLNR (0.49) | ALDH1A1LMNAAPLNRHTR2AHTR2C | |
| SCHEMBL25341773 | 0.74 | GAA (0.40) | GAAALDH1A1KDM4ETDP1KMT2A | |
| SCHEMBL25980741 | 0.72 | GAA (0.38) | GAAALDH1A1KDM4ETDP1KMT2A | |
| SCHEMBL25980752 | 0.71 | APLNR (0.44) | ALDH1A1KMT2ALMNAMEN1APLNR | |
| Hydrochloric Acid SCHEMBL25342899 | 0.70 | APLNR (0.44) | ALDH1A1KMT2ALMNAMEN1APLNR | |
| Hydrochloric Acid SCHEMBL30479625 | 0.70 | APLNR (0.44) | ALDH1A1KMT2ALMNAMEN1APLNR | |
| SCHEMBL21180517 | 0.67 | ALDH1A1 (0.45) | GAAALDH1A1KDM4ETDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023148501-A1 | HETEROCYCLIC DERIVATIVES AS MALT1 INHIBITORS | C4X DISCOVERY LIMITED (GB) | 2023-08-10 | — | — | WO | disclosed |