Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | HTR2C | P28335 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 7/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 7/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 7/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.37 |
| ▸ | USP2 | O75604 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30479625 | 0.99 | APLNR (0.44) | APLNRHTR2AHTR2CTSHRALDH1A1 | |
| Hydrochloric Acid SCHEMBL25342899 | 0.99 | APLNR (0.44) | APLNRHTR2AHTR2CTSHRALDH1A1 | |
| SCHEMBL25980680 | 0.88 | APLNR (0.50) | APLNRHTR2AHTR2CTSHRALDH1A1 | |
| Hydrochloric Acid SCHEMBL25342537 | 0.87 | APLNR (0.49) | APLNRHTR2AHTR2CTSHRALDH1A1 | |
| SCHEMBL30479644 | 0.79 | HTR2A (0.54) | APLNRHTR2AHTR2CTSHRALDH1A1 | |
| SCHEMBL25343094 | 0.79 | HTR2A (0.54) | APLNRHTR2AHTR2CTSHRALDH1A1 | |
| SCHEMBL25341773 | 0.79 | GAA (0.40) | TSHRALDH1A1NPSR1MEN1KMT2A | |
| SCHEMBL25980741 | 0.76 | GAA (0.38) | TSHRALDH1A1NPSR1MEN1KMT2A | |
| SCHEMBL25341754 | 0.72 | APLNR (0.63) | APLNRHTR2AHTR2CMEN1KMT2A | |
| SCHEMBL25980671 | 0.71 | GAA (0.40) | APLNRHTR2AHTR2CTSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023148501-A1 | HETEROCYCLIC DERIVATIVES AS MALT1 INHIBITORS | C4X DISCOVERY LIMITED (GB) | 2023-08-10 | — | — | WO | disclosed |