Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 7/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.32 |
| ▸ | CETP | P11597 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25341773 | 0.90 | GAA (0.40) | GAAALDH1A1KDM4ETDP1MEN1 | |
| SCHEMBL25980674 | 0.89 | GAA (0.39) | GAAALDH1A1KDM4ETDP1MEN1 | |
| SCHEMBL25345233 | 0.79 | POLB (0.43) | GAAALDH1A1KDM4ETDP1MEN1 | |
| SCHEMBL30479647 | 0.76 | ALDH1A1 (0.42) | GAAALDH1A1KDM4ETDP1MEN1 | |
| SCHEMBL25980663 | 0.76 | ALDH1A1 (0.42) | GAAALDH1A1KDM4ETDP1MEN1 | |
| SCHEMBL25980752 | 0.76 | APLNR (0.44) | ALDH1A1MEN1KMT2ATSHRNPSR1 | |
| Hydrochloric Acid SCHEMBL30479625 | 0.75 | APLNR (0.44) | ALDH1A1MEN1KMT2ATSHRNPSR1 | |
| Hydrochloric Acid SCHEMBL25342899 | 0.75 | APLNR (0.44) | ALDH1A1MEN1KMT2ATSHRNPSR1 | |
| SCHEMBL25980671 | 0.72 | GAA (0.40) | GAAALDH1A1KDM4ETDP1MEN1 | |
| SCHEMBL192119 | 0.72 | ALDH1A1 (0.45) | GAAALDH1A1KDM4ETDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4472734-A1 | HETEROCYCLIC DERIVATIVES AS MALT1 INHIBITORS | C4X Discovery Limited (GB) | 2024-12-11 | — | — | EP | disclosed |
| WO-2023148501-A1 | HETEROCYCLIC DERIVATIVES AS MALT1 INHIBITORS | C4X DISCOVERY LIMITED (GB) | 2023-08-10 | — | — | WO | disclosed |
| WO-2023148501-A1 | HETEROCYCLIC DERIVATIVES AS MALT1 INHIBITORS | C4X DISCOVERY LIMITED (GB) | 2023-08-10 | — | — | WO | disclosed |