Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.41 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.39 |
| ▸ | HTR2B | P41595 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | MLNR | O43193 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9805244 | 1.00 | LTA4H (0.44) | LTA4HFAAHMGLLLMNATSHR | |
| SCHEMBL18417879 | 1.00 | LTA4H (0.44) | LTA4HFAAHMGLLLMNATSHR | |
| SCHEMBL706190 | 0.92 | LTA4H (0.46) | LTA4HFAAHMGLLTSHRALDH1A1 | |
| SCHEMBL17391409 | 0.85 | LTA4H (0.44) | LTA4HFAAHMGLLLMNATSHR | |
| SCHEMBL704364 | 0.84 | LMNA (0.38) | LTA4HLMNAALDH1A1TP53ESR1 | |
| SCHEMBL17633823 | 0.83 | LTA4H (0.46) | LTA4HFAAHMGLLLMNATSHR | |
| SCHEMBL680274 | 0.83 | LTA4H (0.46) | LTA4HFAAHMGLLLMNATSHR | |
| SCHEMBL11364614 | 0.83 | LTA4H (0.46) | LTA4HFAAHMGLLLMNATSHR | |
| SCHEMBL11445945 | 0.83 | LTA4H (0.46) | LTA4HFAAHMGLLLMNATSHR | |
| SCHEMBL2874011 | 0.83 | LTA4H (0.46) | LTA4HFAAHMGLLLMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8987493-B2 | Process for synthesis of silane dipeptide analogs | Temple University—Of the Commonwealth System of Higher Education (US) | 2015-03-24 | — | — | US | disclosed |
| US-20130096335-A1 | PROCESS FOR SYNTHESIS OF SILANE DIPEPTIDE ANALOGS | TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2013-04-18 | — | — | US | disclosed |
| WO-2011146842-A1 | PROCESS FOR SYNTHESIS OF SILANE DIPEPTIDE ANALOGS | TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2011-11-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130096335-A1 | PROCESS FOR SYNTHESIS OF SILANE DIPEPTIDE ANALOGS | VIP, DNPEP, SSTR4 | LTA4H 596/4885FAAH 4652/4885MGLL 4171/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.