Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 2/20 | 0.32 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.31 |
| ▸ | ATR | Q13535 | 1/20 | 0.31 |
| ▸ | ATRIP | Q8WXE1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26720565 | 0.84 | DGAT1 (0.37) | DGAT1F2RL1ATRATRIP | |
| SCHEMBL26720196 | 0.84 | ATR (0.33) | DGAT1F2RL1ATRATRIP | |
| SCHEMBL31357963 | 0.77 | DGAT1 (0.33) | DGAT1F2RL1 | |
| SCHEMBL29626770 | 0.76 | GRIN1 (0.34) | DGAT1F2RL1 | |
| SCHEMBL2598354 | 0.76 | GRIN1 (0.34) | DGAT1F2RL1 | |
| SCHEMBL2598448 | 0.75 | TGFBR1 (0.40) | — | |
| SCHEMBL2598377 | 0.75 | MPO (0.35) | — | |
| SCHEMBL30304757 | 0.75 | F2RL1 (0.36) | DGAT1F2RL1 | |
| SCHEMBL25049226 | 0.74 | DGAT1 (0.34) | DGAT1F2RL1ATRATRIP | |
| SCHEMBL2598357 | 0.73 | MAPK1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011146287-A1 | PYRAZOLO[4,3-B]PYRIDINE-7-AMINE INHIBITORS OF ALK5 | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-11-24 | — | — | WO | disclosed |