Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25985689 | 0.73 | L3MBTL1 (0.32) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL26375601 | 0.67 | KDM4E (0.31) | KDM4E | |
| SCHEMBL19149967 | 0.66 | ALDH1A1 (0.36) | RECQLSMN1; SMN2BLMALDH1A1HPGD | |
| SCHEMBL20144462 | 0.61 | RECQL (0.40) | RECQLSMN1; SMN2GLABLMALDH1A1 | |
| SCHEMBL3213071 | 0.60 | — | — | |
| SCHEMBL23673842 | 0.60 | ALDH1A1 (0.52) | RECQLSMN1; SMN2GLABLMALDH1A1 | |
| SCHEMBL27451173 | 0.57 | ALDH1A1 (0.49) | RECQLSMN1; SMN2GLABLMALDH1A1 | |
| SCHEMBL5619859 | 0.57 | ALDH1A1 (0.58) | RECQLSMN1; SMN2GLAALDH1A1HPGD | |
| SCHEMBL7916442 | 0.56 | — | — | |
| SCHEMBL13881363 | 0.56 | GRIK1 (0.35) | ALDH1A1HPGDALOX15HSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3870578-B1 | THERAPEUTIC COMPOUNDS | C4X DISCOVERY LTD (GB) | 2023-08-16 | — | — | EP | disclosed |