Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 6/20 | 0.51 |
| ▸ | HTR2A | P28223 | 3/20 | 0.51 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 5/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1520975 | 1.00 | HTR2C (0.51) | HTR2CHTR2ANOTUMALDH1A1KDM4E | |
| SCHEMBL30681350 | 0.77 | OPRM1 (0.48) | HTR2CHTR2ANOTUMALDH1A1HTR2B | |
| SCHEMBL22270895 | 0.76 | AAK1 (0.42) | LMNAHTR1A | |
| SCHEMBL10153943 | 0.73 | HTR2C (0.65) | HTR2CHTR2ANOTUMALDH1A1KDM4E | |
| SCHEMBL4105459 | 0.72 | SIGMAR1 (0.46) | NOTUMALDH1A1SIGMAR1LMNACYP3A4 | |
| SCHEMBL11179442 | 0.71 | HTR2C (0.42) | HTR2CHTR2ANOTUMALDH1A1KDM4E | |
| SCHEMBL18989168 | 0.71 | ACHE (0.38) | HTR2ANOTUMALDH1A1KDM4EPOLB | |
| SCHEMBL1364392 | 0.70 | HTR2C (0.53) | HTR2CHTR2ANOTUMHTR2BSIGMAR1 | |
| SCHEMBL5765145 | 0.69 | HTR2C (0.51) | HTR2CHTR2ANOTUMALDH1A1KDM4E | |
| SCHEMBL21278358 | 0.69 | HTR2A (0.63) | HTR2CHTR2AALDH1A1KDM4EHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230242567-A1 | CHIRAL PHOSPHORAMIDITE AUXILIARIES AND METHODS OF THEIR USE | SIRIUS THERAPEUTICS, INC. | 2023-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230242567-A1 | CHIRAL PHOSPHORAMIDITE AUXILIARIES AND METHODS OF THEIR USE | PNP, PCNA, NUDT14 | HTR2C 2843/4885HTR2A 3138/4885NOTUM 2886/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.