SCHEMBL25989031

SCHEMBL25989031

COc1cc2c(cc1C)OC1(CC(C)(C)c3cc(CO)c(C)cc3O1)CC2(C)C

nearest known ligand 0.38

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
FTO Q9C0B1 2/20 0.38
ALOX15 P16050 1/20 0.36
PDE4A P27815 1/20 0.33
PDE4B Q07343 1/20 0.33
PDE4C Q08493 1/20 0.33
PDE4D Q08499 1/20 0.33
POLA1 P09884 2/20 0.31
FPR1 P21462 1/20 0.31
GNRHR P30968 1/20 0.31
GPR183 P32249 1/20 0.31
GPR119 Q8TDV5 1/20 0.31
TAAR1 Q96RJ0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12919726 0.88 FTO (0.42) FTOTAAR1
SCHEMBL13607174 0.80 FTO (0.38) FTOALOX15POLA1
SCHEMBL3622315 0.80 POLB (0.39) FTO
SCHEMBL13607187 0.78 KMT2A (0.38) FTO
SCHEMBL27362901 0.78 FTO (0.33) FTO
SCHEMBL15867105 0.78 FTO (0.46) FTOALOX15PDE4APDE4BPDE4C
SCHEMBL17264203 0.75 ALOX15 (0.43) ALOX15PDE4APDE4BPDE4CPDE4D
SCHEMBL13607173 0.74 KMT2A (0.37)
SCHEMBL13668327 0.74 MAPT (0.37) FTO
SCHEMBL12758280 0.74 ACHE (0.39) FTOALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11789307-B2 Colorant filter, backlight unit, and liquid crystal display device FUJIFILM CORPORATION (JP) 2023-10-17 US disclosed
US-11733435-B2 Polarizing plate protective film, polarizing plate, and liquid crystal display device FUJIFILM CORPORATION (JP) 2023-08-22 US disclosed