SCHEMBL17264203

SCHEMBL17264203

COc1cc2c(cc1OC)C1(CC(C)(C)c3cc(CO)c(C)cc31)CC2(C)C

nearest known ligand 0.43

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.43
PDE4A P27815 1/20 0.40
PDE4B Q07343 1/20 0.40
PDE4C Q08493 1/20 0.40
PDE4D Q08499 1/20 0.40
GNRHR P30968 3/20 0.38
FPR1 P21462 1/20 0.38
GPR183 P32249 1/20 0.38
GPR119 Q8TDV5 1/20 0.38
RXRA P19793 6/20 0.34
POLA1 P09884 2/20 0.34
PDCD1 Q15116 1/20 0.31
CD274 Q9NZQ7 1/20 0.31
DPP4 P27487 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13447603 0.91 PDE4A (0.49) ALOX15PDE4APDE4BPDE4CPDE4D
SCHEMBL14539423 0.82 ALOX15 (0.40) ALOX15PDE4APDE4BPDE4CPDE4D
SCHEMBL11136773 0.81 CA12 (0.41) ALOX15RXRA
SCHEMBL13712970 0.78 ALOX15 (0.38) ALOX15PDE4APDE4BPDE4CPDE4D
SCHEMBL12110373 0.75 FTO (0.38) RXRA
SCHEMBL25989031 0.75 FTO (0.38) ALOX15PDE4APDE4BPDE4CPDE4D
SCHEMBL13250932 0.74 FTO (0.33) RXRA
SCHEMBL4464547 0.73 FTO (0.39) ALOX15RXRA
SCHEMBL11220334 0.73 ALOX15 (0.51) ALOX15PDE4APDE4BPDE4CPDE4D
SCHEMBL21615710 0.73 KDM4E (0.37) ALOX15PDE4APDE4BPDE4CPDE4D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150330602-A1 WAVE LENGTH CONVERSION MEMBER, BACK LIGHT UNIT, LIQUID CRYSTAL DISPLAY DEVICE, AND QUANTUM DOT-CONTAINING POLYMERIZABLE COMPOSITION FUJIFILM CORPORATION (JP) 2015-11-19 US disclosed