SCHEMBL25989164

SCHEMBL25989164

O=c1c2cc3c(=O)n(-c4ccc([N+](=O)[O-])cc4)c(=O)c3cc2c(=O)n1-c1ccc([N+](=O)[O-])cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.53
CA1 P00915 1/20 0.53
CA2 P00918 1/20 0.53
CA9 Q16790 1/20 0.53
NPC1 O15118 2/20 0.52
GSK3A P49840 1/20 0.50
GSK3B P49841 1/20 0.50
ALDH1A1 P00352 5/20 0.49
HTT P42858 2/20 0.49
POLB P06746 2/20 0.49
MEN1 O00255 1/20 0.49
KMT2A Q03164 1/20 0.49
PLEC Q15149 1/20 0.49
KAT2B Q92831 3/20 0.48
SCN2A Q99250 1/20 0.47
MAPT P10636 2/20 0.46
SRC P12931 1/20 0.46
PRKACA P17612 1/20 0.46
PRKACG P22612 1/20 0.46
PRKACB P22694 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6675514 0.81 CA12 (0.65) CA12CA1CA2CA9NPC1
SCHEMBL9187712 0.79 GSK3A (0.56) GSK3AGSK3BALDH1A1POLBMEN1
SCHEMBL28866731 0.76 MAPT (0.54) ALDH1A1POLBMEN1KMT2AKAT2B
SCHEMBL517098 0.74 GSK3A (0.52) GSK3AGSK3BALDH1A1HTTPOLB
SCHEMBL6982431 0.73 TP53 (0.57) CA12CA9NPC1GSK3BALDH1A1
SCHEMBL760529 0.73 CA12 (0.57) CA12CA1CA2CA9ALDH1A1
SCHEMBL28604247 0.72 HSD17B10 (0.56) CA12CA1CA2CA9GSK3A
SCHEMBL3107098 0.72 ATM (0.55) NPC1ALDH1A1HTTPOLBMEN1
SCHEMBL21219645 0.72 SIRT6 (0.46) CA12CA9GSK3AGSK3BALDH1A1
SCHEMBL29525910 0.72 ATM (0.55) NPC1ALDH1A1HTTPOLBMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11789307-B2 Colorant filter, backlight unit, and liquid crystal display device FUJIFILM CORPORATION (JP) 2023-10-17 US disclosed
US-11733435-B2 Polarizing plate protective film, polarizing plate, and liquid crystal display device FUJIFILM CORPORATION (JP) 2023-08-22 US disclosed