Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 1/20 | 0.56 |
| ▸ | GSK3B | P49841 | 1/20 | 0.56 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PLEC | Q15149 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11364832 | 0.83 | MAPT (0.59) | GSK3AGSK3BSCN2AMAPTALDH1A1 | |
| SCHEMBL11365363 | 0.83 | MAPT (0.54) | GSK3AGSK3BSCN2AMAPTALDH1A1 | |
| SCHEMBL11369430 | 0.82 | MAPT (0.62) | GSK3AGSK3BMAPTALDH1A1GAA | |
| SCHEMBL517098 | 0.81 | GSK3A (0.52) | GSK3AGSK3BSCN2AMAPTALDH1A1 | |
| SCHEMBL11608010 | 0.80 | GSK3A (0.44) | GSK3AGSK3BSCN2AMAPTALDH1A1 | |
| SCHEMBL25989164 | 0.79 | CA12 (0.53) | GSK3AGSK3BSCN2AMAPTALDH1A1 | |
| SCHEMBL28604247 | 0.78 | HSD17B10 (0.56) | GSK3AGSK3BSCN2AMAPTALDH1A1 | |
| SCHEMBL21219645 | 0.78 | SIRT6 (0.46) | GSK3AGSK3BSCN2AMAPTALDH1A1 | |
| SCHEMBL9473177 | 0.78 | GSK3A (0.52) | GSK3AGSK3BMAPTALDH1A1MAPK1 | |
| SCHEMBL11832703 | 0.78 | HSPB1 (0.50) | GSK3AGSK3BMAPTALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0447074-B1 | Catalytic isocyanate trimerization and urethane formation | ASAHI DENKA KOGYO KK (JP) | 1995-12-13 | — | — | EP | disclosed |
| US-5264572-A | Catalyst for isocyanate trimerization | ASAHI DENKA KOGYO K.K. (JP) | 1993-11-23 | — | — | US | disclosed |
| EP-0447074-A2 | Catalytic isocyanate trimerization and urethane formation | ASAHI DENKA KOGYO KABUSHIKI KAISHA (JP) | 1991-09-18 | — | — | EP | disclosed |