Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | JAK2 | O60674 | 1/20 | 0.54 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.54 |
| ▸ | MELK | Q14680 | 1/20 | 0.54 |
| ▸ | STK24 | Q9Y6E0 | 1/20 | 0.54 |
| ▸ | TYMS | P04818 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | APEX1 | P27695 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NOS1 | P29475 | 2/20 | 0.42 |
| ▸ | NOS2 | P35228 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10463259 | 0.81 | TYMS (0.46) | ALDH1A1JAK2RPS6KA3MELKSTK24 | |
| SCHEMBL187697 | 0.79 | ALDH1A1 (0.61) | ALDH1A1TYMSKDM4EMEN1MAPT | |
| SCHEMBL29626558 | 0.79 | ALDH1A1 (0.61) | ALDH1A1TYMSKDM4EMEN1MAPT | |
| SCHEMBL259909 | 0.77 | TDP1 (0.54) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL9056779 | 0.74 | ALDH1A1 (0.52) | ALDH1A1TYMSKDM4EMEN1MAPT | |
| SCHEMBL30098446 | 0.74 | ALDH1A1 (1.00) | ALDH1A1KDM4EMEN1KMT2AGAA | |
| SCHEMBL307488 | 0.74 | ALDH1A1 (1.00) | ALDH1A1KDM4EMEN1KMT2AGAA | |
| SCHEMBL487276 | 0.74 | ALDH1A1 (0.59) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL4717435 | 0.73 | NOS1 (0.64) | ALDH1A1TYMSKDM4EMEN1MAPT | |
| SCHEMBL15801718 | 0.72 | ALDH1A1 (0.42) | ALDH1A1TYMSKDM4EMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998051307-A1 | METHODS FOR TREATING INFLAMMATION, INFLAMMATORY DISEASES, ARTHRITIS AND STROKE USING pADPRT INHIBITORS | OCTAMER, INC. (US) | 1998-11-19 | — | — | WO | claimed |
| US-5877185-A | THERAPY FOR CANCER OR RETROVIRUS | OCTAMER, INC. (US) | 1999-03-02 | — | — | US | disclosed |
| US-5670518-A | ANTITUMOR AGENTS; VIRICIDES | OCTAMER, INC. | 1997-09-23 | — | — | US | disclosed |
| WO-1996022791-A9 | NOVEL SYNERGISTIC COMPOSITIONS USEFUL AS ANTI-TUMOR OR ANTI-RETROVIRAL AGENTS | — | 1996-10-03 | — | — | WO | disclosed |
| WO-1996022791-A1 | NOVEL SYNERGISTIC COMPOSITIONS USEFUL AS ANTI-TUMOR OR ANTI-RETROVIRAL AGENTS | OCTAMER, INC. (US) | 1996-08-01 | — | — | WO | disclosed |