Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100A4 | P26447 | 5/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | APAF1 | O14727 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | GUCY1B2 | O75343 | 1/20 | 0.50 |
| ▸ | GUCY1A2 | P33402 | 1/20 | 0.50 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.50 |
| ▸ | GUCY1B1 | Q02153 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | NSD2 | O96028 | 5/20 | 0.49 |
| ▸ | TDP2 | O95551 | 4/20 | 0.49 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.44 |
| ▸ | NQO1 | P15559 | 3/20 | 0.43 |
| ▸ | G6PD | P11413 | 2/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2599332 | 0.83 | S100A4 (0.71) | S100A4ALDH1A1APAF1MAPTMEN1 | |
| SCHEMBL10505442 | 0.82 | S100A4 (0.70) | S100A4ALDH1A1APAF1MAPTSMN1; SMN2 | |
| SCHEMBL458428 | 0.81 | S100A4 (0.68) | S100A4ALDH1A1APAF1MAPTMEN1 | |
| SCHEMBL8371686 | 0.79 | S100A4 (0.65) | S100A4ALDH1A1APAF1NSD2TDP2 | |
| SCHEMBL15698467 | 0.78 | S100A4 (0.63) | S100A4ALDH1A1APAF1MAPTMEN1 | |
| SCHEMBL18921849 | 0.75 | MAPT (0.60) | S100A4ALDH1A1APAF1MAPTMEN1 | |
| SCHEMBL10509896 | 0.73 | KMT2A (0.58) | S100A4ALDH1A1MAPTMEN1GUCY1B2 | |
| SCHEMBL12181932 | 0.73 | S100A4 (1.00) | S100A4ALDH1A1MAPTMEN1GUCY1B2 | |
| SCHEMBL7720493 | 0.73 | S100A4 (0.57) | S100A4ALDH1A1APAF1MAPTMEN1 | |
| SCHEMBL21814444 | 0.72 | ALDH1A1 (0.79) | S100A4ALDH1A1APAF1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130090355-A1 | CHEMICAL AGENTS FOR THE PREVENTION OF INHIBITION OR TUMOR METASTASIS | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2013-04-11 | — | — | US | claimed |
| WO-2011146101-A1 | CHEMICAL AGENTS FOR THE PREVENTION OR INHIBITION OF TUMOR METASTASIS | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2011-11-24 | — | — | WO | claimed |
| US-20130090355-A1 | CHEMICAL AGENTS FOR THE PREVENTION OF INHIBITION OR TUMOR METASTASIS | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2013-04-11 | — | — | US | disclosed |
| US-20130090355-A1 | CHEMICAL AGENTS FOR THE PREVENTION OF INHIBITION OR TUMOR METASTASIS | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2013-04-11 | — | — | US | disclosed |
| US-20130090355-A1 | CHEMICAL AGENTS FOR THE PREVENTION OF INHIBITION OR TUMOR METASTASIS | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2013-04-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130090355-A1 | CHEMICAL AGENTS FOR THE PREVENTION OF INHIBITION OR TUMOR METASTASIS | S100A4, S100A6, S100A10 | S100A4 1/4885ALDH1A1 2312/4885APAF1 1154/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.