Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 8/20 | 0.43 |
| ▸ | F2 | P00734 | 2/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.42 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.42 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KCNH3 | Q9ULD8 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26005514 | 0.81 | NAMPT (0.40) | PRSS1F2PRSS2PRSS3TMPRSS6 | |
| SCHEMBL17561644 | 0.78 | PRSS1 (0.49) | PRSS1F2ST14SMN1; SMN2NPC1 | |
| SCHEMBL4161233 | 0.77 | ALDH1A1 (0.61) | SMN1; SMN2NPC1RAB9AGAAMAPT | |
| SCHEMBL13545923 | 0.77 | SMN1; SMN2 (0.56) | SMN1; SMN2NPC1THRBRAB9AMAPT | |
| SCHEMBL128126 | 0.76 | MAPT (0.47) | KCNH3GAAMAPTALDH1A1TDP1 | |
| SCHEMBL3248482 | 0.76 | ADRA2A (0.54) | PRSS1F2PRSS2PRSS3TMPRSS6 | |
| Hydrochloric Acid SCHEMBL9680720 | 0.74 | KCNH3 (0.49) | KCNH3GAAMAPTALDH1A1TDP1 | |
| Hydrochloric Acid SCHEMBL3337783 | 0.74 | KCNH3 (0.49) | KCNH3GAAMAPTALDH1A1TDP1 | |
| SCHEMBL1996992 | 0.74 | F2 (0.50) | PRSS1F2PRSS2PRSS3TMPRSS6 | |
| SCHEMBL3062486 | 0.74 | KCNH3 (0.65) | SMN1; SMN2NPC1RAB9AKCNH3GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023152773-A1 | SOLID FORMS OF MOMELOTINIB SALTS AND IMPROVED PROCESSES FOR THE PREPARATION OF MOMELOTINIB | DR. REDDY'S INSTITUTE OF LIFE SCIENCES (IN) | 2023-08-17 | — | — | WO | disclosed |