Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 13/20 | 1.00 |
| ▸ | S100A4 | P26447 | 6/20 | 1.00 |
| ▸ | MAP2K7 | O14733 | 4/20 | 0.63 |
| ▸ | CDC25A | P30304 | 4/20 | 0.63 |
| ▸ | CDC25B | P30305 | 4/20 | 0.63 |
| ▸ | ELANE | P08246 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7106792 | 0.86 | SOAT1 (1.00) | SOAT1S100A4MAP2K7CDC25ACDC25B | |
| SCHEMBL2599427 | 0.83 | SOAT1 (1.00) | SOAT1S100A4MAP2K7CDC25ACDC25B | |
| SCHEMBL15732841 | 0.82 | SOAT1 (1.00) | SOAT1S100A4MAP2K7CDC25ACDC25B | |
| SCHEMBL15732931 | 0.80 | SOAT1 (1.00) | SOAT1S100A4MAP2K7CDC25ACDC25B | |
| SCHEMBL15732808 | 0.80 | SOAT1 (1.00) | SOAT1S100A4MAP2K7CDC25ACDC25B | |
| SCHEMBL15732984 | 0.80 | SOAT1 (1.00) | SOAT1S100A4MAP2K7CDC25ACDC25B | |
| SCHEMBL15732972 | 0.80 | SOAT1 (1.00) | SOAT1S100A4MAP2K7CDC25ACDC25B | |
| SCHEMBL358334 | 0.80 | SOAT1 (1.00) | SOAT1S100A4MAP2K7CDC25ACDC25B | |
| SCHEMBL16884397 | 0.79 | SOAT1 (0.71) | SOAT1S100A4MAP2K7CDC25ACDC25B | |
| SCHEMBL2599403 | 0.79 | S100A4 (1.00) | SOAT1S100A4MAP2K7CDC25ACDC25B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130090355-A1 | CHEMICAL AGENTS FOR THE PREVENTION OF INHIBITION OR TUMOR METASTASIS | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2013-04-11 | — | — | US | claimed |
| WO-2011146101-A1 | CHEMICAL AGENTS FOR THE PREVENTION OR INHIBITION OF TUMOR METASTASIS | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2011-11-24 | — | — | WO | claimed |
| EP-3182129-B1 | METHOD OF SCREENING A THERAPEUTIC AGENT FOR K-RAS MUTANT CANCER | RAND BIO SCIENCE INC (KR) | 2018-12-26 | — | — | EP | disclosed |
| EP-3182129-A1 | CHEMICAL INHIBITOR OF P53-SNAIL BINDING AND PHARMACEUTICAL COMPOSITION FOR TREATING CANCER DISEASE CONTAINING SAME AS ITS ACTIVE INGREDIENT | RAND Bio Science Inc. (KR) | 2017-06-21 | — | — | EP | disclosed |
| US-9400281-B2 | Method of screening of therapeutic agents for K-Ras mutant driven cancers | PUSAN NATIONAL UNIVERSITY INDUSTRY-UNIVERSITY COOPERATION FOUNDATION (KR) | 2016-07-26 | — | — | US | disclosed |
| US-20140147866-A1 | COMPOUND FOR INHIBITING SNAIL-P53 BINDING AND THERAPEUTIC AGENT FOR CANCER INCLUDING THE COMPOUND AS EFFECTIVE COMPONENT | THE INDUSTRY & ACADEMIC COOPERATION IN CHUNGNAM NATIONAL UNIVERSITY (KR) | 2014-05-29 | — | — | US | disclosed |
| US-20130090355-A1 | CHEMICAL AGENTS FOR THE PREVENTION OF INHIBITION OR TUMOR METASTASIS | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2013-04-11 | — | — | US | disclosed |
| US-20130090355-A1 | CHEMICAL AGENTS FOR THE PREVENTION OF INHIBITION OR TUMOR METASTASIS | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2013-04-11 | — | — | US | disclosed |
| US-20130090355-A1 | CHEMICAL AGENTS FOR THE PREVENTION OF INHIBITION OR TUMOR METASTASIS | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2013-04-11 | — | — | US | disclosed |
| WO-2011146101-A1 | CHEMICAL AGENTS FOR THE PREVENTION OR INHIBITION OF TUMOR METASTASIS | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2011-11-24 | — | — | WO | disclosed |
| WO-2011146101-A1 | CHEMICAL AGENTS FOR THE PREVENTION OR INHIBITION OF TUMOR METASTASIS | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2011-11-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130090355-A1 | CHEMICAL AGENTS FOR THE PREVENTION OF INHIBITION OR TUMOR METASTASIS | S100A4, S100A6, S100A10 | SOAT1 3535/4885S100A4 1/4885MAP2K7 4152/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.