Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100A4 | P26447 | 7/20 | 1.00 |
| ▸ | SOAT1 | P35610 | 13/20 | 0.71 |
| ▸ | CDC25A | P30304 | 4/20 | 0.69 |
| ▸ | CDC25B | P30305 | 4/20 | 0.69 |
| ▸ | MAP2K7 | O14733 | 3/20 | 0.69 |
| ▸ | STAT3 | P40763 | 1/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | APAF1 | O14727 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | GMNN | O75496 | 1/20 | 0.61 |
| ▸ | TDP2 | O95551 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4629512 | 0.86 | S100A4 (0.76) | S100A4SOAT1CDC25ACDC25BMAP2K7 | |
| SCHEMBL16884397 | 0.83 | SOAT1 (0.71) | S100A4SOAT1CDC25ACDC25BMAP2K7 | |
| SCHEMBL7106792 | 0.83 | SOAT1 (1.00) | S100A4SOAT1CDC25ACDC25BMAP2K7 | |
| SCHEMBL2599351 | 0.82 | S100A4 (1.00) | S100A4SOAT1CDC25ACDC25BMAP2K7 | |
| SCHEMBL9270311 | 0.81 | S100A4 (0.76) | S100A4SOAT1CDC25ACDC25BMAP2K7 | |
| SCHEMBL2599427 | 0.80 | SOAT1 (1.00) | S100A4SOAT1CDC25ACDC25BMAP2K7 | |
| SCHEMBL9267240 | 0.80 | S100A4 (0.69) | S100A4SOAT1CDC25ACDC25BMAP2K7 | |
| SCHEMBL15732841 | 0.79 | SOAT1 (1.00) | S100A4SOAT1CDC25ACDC25BMAP2K7 | |
| SCHEMBL2599376 | 0.79 | SOAT1 (1.00) | S100A4SOAT1CDC25ACDC25BMAP2K7 | |
| SCHEMBL18191031 | 0.78 | CDC25B (1.00) | S100A4SOAT1CDC25ACDC25BMAP2K7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130090355-A1 | CHEMICAL AGENTS FOR THE PREVENTION OF INHIBITION OR TUMOR METASTASIS | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2013-04-11 | — | — | US | claimed |
| WO-2011146101-A1 | CHEMICAL AGENTS FOR THE PREVENTION OR INHIBITION OF TUMOR METASTASIS | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2011-11-24 | — | — | WO | claimed |
| US-20150192852-A1 | LITHOGRAPHIC PRINTING PLATE PRECURSOR AND PLATE MAKING METHOD | FUJIFILM CORPORATION (JP) | 2015-07-09 | — | — | US | disclosed |
| WO-2014045783-A1 | ORIGINAL PLANOGRAPHIC PRINTING PLATE, AND PLATE MAKING METHOD | 富士フイルム株式会社 (JP) | 2014-03-27 | — | — | WO | disclosed |
| US-20130090355-A1 | CHEMICAL AGENTS FOR THE PREVENTION OF INHIBITION OR TUMOR METASTASIS | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2013-04-11 | — | — | US | disclosed |
| US-20130090355-A1 | CHEMICAL AGENTS FOR THE PREVENTION OF INHIBITION OR TUMOR METASTASIS | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2013-04-11 | — | — | US | disclosed |
| US-20130090355-A1 | CHEMICAL AGENTS FOR THE PREVENTION OF INHIBITION OR TUMOR METASTASIS | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2013-04-11 | — | — | US | disclosed |
| US-20120135013-A1 | CD45 and Methods and Compounds Related Thereto | ARMY, UNITED STATES | 2012-05-31 | — | — | US | disclosed |
| US-20120135013-A1 | CD45 and Methods and Compounds Related Thereto | ARMY, UNITED STATES | 2012-05-31 | — | — | US | disclosed |
| WO-2011146101-A1 | CHEMICAL AGENTS FOR THE PREVENTION OR INHIBITION OF TUMOR METASTASIS | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2011-11-24 | — | — | WO | disclosed |
| WO-2000008495-A2 | ANTIPROLIFERATIVE NAPHTHOQUINONES, DERIVATIVES, COMPOSITIONS, AND USES THEREOF | UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2000-02-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130090355-A1 | CHEMICAL AGENTS FOR THE PREVENTION OF INHIBITION OR TUMOR METASTASIS | S100A4, S100A6, S100A10 | S100A4 1/4885SOAT1 3535/4885CDC25A 248/4885 |
| US-20120135013-A1 | CD45 and Methods and Compounds Related Thereto | PTPRC, PTPRO, PTPRCAP | S100A4 630/4885SOAT1 3805/4885CDC25A 182/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.