Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.32 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.32 |
| ▸ | KMO | O15229 | 1/20 | 0.31 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.31 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.31 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.31 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.31 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.31 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2599618 | 0.85 | TDP1 (0.36) | TDP1CYP3A4MEN1KMT2AALDH1A1 | |
| SCHEMBL12182363 | 0.81 | KDM4E (0.45) | ALDH1A1SMN1; SMN2LMNAHSD17B10MAPT | |
| SCHEMBL116082 | 0.78 | TDP1 (0.50) | TDP1CYP3A4MEN1KMT2AALDH1A1 | |
| SCHEMBL3218994 | 0.78 | TDP1 (0.50) | TDP1CYP3A4MEN1KMT2AALDH1A1 | |
| SCHEMBL29390992 | 0.78 | TDP1 (0.50) | TDP1CYP3A4MEN1KMT2AALDH1A1 | |
| Potassium SCHEMBL30575490 | 0.77 | TDP1 (0.48) | TDP1CYP3A4MEN1KMT2AALDH1A1 | |
| SCHEMBL28002634 | 0.77 | TDP1 (0.48) | TDP1CYP3A4MEN1KMT2AALDH1A1 | |
| SCHEMBL1404403 | 0.77 | TDP1 (0.48) | TDP1CYP3A4MEN1KMT2AALDH1A1 | |
| SCHEMBL19627732 | 0.77 | TDP1 (0.40) | TDP1CYP3A4MEN1KMT2AALDH1A1 | |
| SCHEMBL16857047 | 0.76 | TDP1 (0.40) | TDP1CYP3A4MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2571852-A1 | CHEMICAL COMPOUNDS | Syngenta Limited (GB) | 2013-03-27 | — | — | EP | disclosed |
| US-20130065757-A1 | CHEMICAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2013-03-14 | — | — | US | disclosed |
| WO-2011144891-A1 | CHEMICAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2011-11-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130065757-A1 | CHEMICAL COMPOUNDS | HPD, PPOX, PIN1 | TDP1 2573/4885CYP3A4 622/4885MEN1 3392/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.