Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | ASPH | Q12797 | 1/20 | 0.36 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.36 |
| ▸ | GABRP | O00591 | 3/20 | 0.36 |
| ▸ | GABRD | O14764 | 3/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.36 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.36 |
| ▸ | GABRE | P78334 | 3/20 | 0.36 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.36 |
| ▸ | GABRG1 | Q8N1C3 | 3/20 | 0.36 |
| ▸ | GABRG3 | Q99928 | 3/20 | 0.36 |
| ▸ | GABRQ | Q9UN88 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL442311 | 0.77 | KDM4E (0.40) | KDM4EASPHKDM8GABRPGABRD | |
| SCHEMBL6200703 | 0.69 | KDM4E (0.41) | KDM4EASPHKDM8GABRPGABRD | |
| SCHEMBL6197961 | 0.68 | KDM4E (0.43) | KDM4EASPHKDM8GABRPGABRD | |
| SCHEMBL438922 | 0.68 | KDM4E (0.53) | KDM4EGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL440378 | 0.68 | HAVCR2 (0.49) | KDM4EGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL436994 | 0.67 | HAVCR2 (0.48) | KDM4EASPHKDM8GABRPGABRD | |
| SCHEMBL29549879 | 0.67 | EGFR (0.42) | KDM4EHPGD | |
| SCHEMBL27053764 | 0.66 | KEAP1 (0.44) | KDM4EASPHKDM8KMT2AHPGD | |
| SCHEMBL27053779 | 0.66 | KDM4E (0.46) | KDM4EASPHKDM8GABRPGABRD | |
| SCHEMBL10466610 | 0.66 | KDM4E (0.41) | KDM4EASPHKDM8GABRPGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219499-A1 | A CLASS OF FUSED RING COMPOUNDS, AND PREPARATION AND USE THEREOF | CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co., Ltd. (CN) | 2023-08-02 | — | — | EP | disclosed |