Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.48 |
| ▸ | BTK | Q06187 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | TEC | P42680 | 1/20 | 0.41 |
| ▸ | ITK | Q08881 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ASPH | Q12797 | 2/20 | 0.39 |
| ▸ | KDM8 | Q8N371 | 2/20 | 0.39 |
| ▸ | GABRP | O00591 | 3/20 | 0.38 |
| ▸ | GABRD | O14764 | 3/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6198912 | 0.81 | MAPT (0.43) | HAVCR2MAPTKDM4EKMT2AASPH | |
| SCHEMBL436633 | 0.78 | HAVCR2 (0.68) | HAVCR2BTKKDM4EKMT2AASPH | |
| SCHEMBL436943 | 0.78 | HAVCR2 (0.56) | HAVCR2BTKMAPTKDM4EKMT2A | |
| SCHEMBL28902617 | 0.75 | BTK (0.51) | HAVCR2BTKMAPTFYNSRC | |
| SCHEMBL438132 | 0.73 | GABRP (0.49) | HAVCR2BTKMAPTKDM4EKMT2A | |
| SCHEMBL440068 | 0.73 | HAVCR2 (0.63) | HAVCR2MAPTKDM4EKMT2AGABRP | |
| SCHEMBL439646 | 0.72 | HAVCR2 (0.32) | HAVCR2BTK | |
| SCHEMBL438931 | 0.71 | HAVCR2 (0.49) | HAVCR2KDM4EKMT2AASPHKDM8 | |
| SCHEMBL442311 | 0.71 | KDM4E (0.40) | HAVCR2KDM4EKMT2AASPHKDM8 | |
| SCHEMBL26167963 | 0.70 | HAVCR2 (0.54) | HAVCR2MAPTKDM4EKMT2AASPH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |